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1. WO2009015363 - ZEARALENONE MACROLIDE DERIVATIVES AND USES OF THE SAME

Publication Number WO/2009/015363
Publication Date 29.01.2009
International Application No. PCT/US2008/071248
International Filing Date 25.07.2008
IPC
C07D 313/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
313Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
A61K 31/365 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
365Lactones
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 313/00
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
313Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
Applicants
  • EISAI R & D MANAGEMENT CO., LTD. [JP]/[JP] (AllExceptUS)
  • DU, Hong [CN]/[US] (UsOnly)
  • WANG, John (Yuan) [US]/[US] (UsOnly)
Inventors
  • DU, Hong
  • WANG, John (Yuan)
Agents
  • HANLEY, Elizabeth, A.
Priority Data
60/951,89225.07.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ZEARALENONE MACROLIDE DERIVATIVES AND USES OF THE SAME
(FR) DÉRIVÉS DU MACROLIDE ZÉARALÉNONE ET LEURS UTILISATIONS
Abstract
(EN)
The present invention provides compounds, pharmaceutical compositions and methods for the treatment of specific cancers. Such compositions may generally comprise a compound of formula (I) wherein R3-R6, R8-R10, R13 and Y are as defined herein, or pharmaceutically acceptable salts or esters thereof; and a pharmaceutically acceptable carrier.
(FR)
La présente invention concerne des composés, des compositions pharmaceutiques et des procédés destinés à traiter des cancers spécifiques. De telles compositions peuvent généralement comprendre un composé représenté par la formule (I) dans laquelle R3-R6, R8-R10, R13 et Y sont tels que définis ici, ou des sels ou des esters pharmaceutiquement acceptables de celui-ci ; et un transporteur pharmaceutiquement acceptable.
Also published as
Latest bibliographic data on file with the International Bureau