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1. WO2009014061 - EMULSION COMPOSITIONS

Publication Number WO/2009/014061
Publication Date 29.01.2009
International Application No. PCT/JP2008/062912
International Filing Date 17.07.2008
IPC
A61K 31/685 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
66Phosphorus compounds
683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
685one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 8/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
02characterised by special physical form
04Dispersions; Emulsions
06Emulsions
A61K 8/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
33containing oxygen
34Alcohols
A61K 8/55 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
55containing phosphorus
A61K 8/72 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
A61K 8/92 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products
CPC
A61K 31/01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
01Hydrocarbons
A61K 31/045
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
A61K 31/125
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
12Ketones
122having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
125Camphor; Nuclear substituted derivatives thereof
A61K 31/135
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
A61K 31/167
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
165having aromatic rings, e.g. colchicine, atenolol, progabide
167having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 31/17
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
17having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
Applicants
  • ロート製薬株式会社 ROHTO PHARMACEUTICAL CO., LTD. [JP]/[JP] (AllExceptUS)
  • 阿部 正通 ABE, Masamichi [JP]/[JP] (UsOnly)
  • 石川 敬 ISHIKAWA, Takashi [JP]/[JP] (UsOnly)
  • 片野 高 KATANO, Takashi [JP]/[JP] (UsOnly)
  • 丸川 純子 MARUKAWA, Junko [JP]/[JP] (UsOnly)
  • 春日 慎也 KASUGA, Shinya [JP]/[JP] (UsOnly)
Inventors
  • 阿部 正通 ABE, Masamichi
  • 石川 敬 ISHIKAWA, Takashi
  • 片野 高 KATANO, Takashi
  • 丸川 純子 MARUKAWA, Junko
  • 春日 慎也 KASUGA, Shinya
Agents
  • 鈴木 俊一郎 SUZUKI, Shunichiro
Priority Data
2007-19021620.07.2007JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) EMULSION COMPOSITIONS
(FR) COMPOSITIONS D'ÉMULSION
(JA) 乳化組成物
Abstract
(EN)
The invention aims at providing an emulsion composition which is improved in skin occlusion and is excellent in feelings in use in spite of its containing vaseline in an amount enough to inhibit the transpiration of water from the skin and which has satisfactory skin-moisturizing effect and persistent excellent humectant effect and exhibits both low irritativeness and excellent storage stability and an emulsion composition having mite-repellent activity. An emulsion composition comprising (A) vaseline, (B) lecithin, (C) glycerol, (D) water, and (E) a water-soluble polymer, characterized in that the content of vaseline (A) is 10 to 30wt% based on the emulsion composition (as calculated by taking the weight of the composition as 100 wt%) and that the inner phase of the emulsion composition has a mean particle diameter of 800nm or below as determined by dynamic light scattering method on the basis of dynamic light scattering theory.
(FR)
L'invention concerne une composition d'émulsion ayant une occlusion de la peau améliorée et d'excellentes sensations en utilisation malgré le fait qu'elle contient de la vaseline dans une quantité suffisante pour inhiber la transpiration de l'eau à partir de la peau et qui a un effet d'hydratation de la peau satisfaisant, et un excellent effet humidifiant persistant et présente à la fois une capacité d'irritation faible et une excellente stabilité au stockage et une composition d'émulsion ayant une activité antimite. Une composition d'émulsion comprend (A) de la vaseline, (B) de la lécithine, (C) du glycérol, (D) de l'eau et (E) un polymère soluble dans l'eau, caractérisé par le fait que la teneur en vaseline (A) est de 10 à 30 % en poids sur la base de la composition d'émulsion (telle que calculée en prenant le poids de la composition comme étant 100 % en poids) et par le fait que la phase interne de la composition d'émulsion a un diamètre de particule moyen de 800 nm ou moins tel que déterminé par un procédé de diffusion de lumière dynamique sur la base d'une théorie de diffusion de lumière dynamique.
(JA)
 本発明は、皮膚の閉塞性を向上させ、皮膚からの水分蒸散を低減するために十分な量のワセリンを含有しながらも使用感に優れ、皮膚に十分な水分を与えることができ、かつ持続的で良好な保湿性を有し、さらに低刺激性と保存安定性とを兼ね備えた乳化組成物を提供することを目的とする。さらに、本発明はダニ忌避作用を有する乳化組成物を提供することも目的とする。  本発明の乳化組成物は、(A)ワセリン、(B)レシチン、(C)グリセリン、(D)水及び(E)水溶性高分子を含有する乳化組成物であって、該ワセリン(A)の含有量が前記乳化組成物100重量%に対して10~30重量%であり、前記乳化組成物の内相の、動的光散乱法により動的光散乱理論に基づいて測定した平均粒径が800nm以下であることを特徴としている。
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