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1. WO2009010298 - PAULLONE DERIVATIVES AND ITS USE

Publication Number WO/2009/010298
Publication Date 22.01.2009
International Application No. PCT/EP2008/005908
International Filing Date 18.07.2008
IPC
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
A61K 31/55 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
55having seven-membered rings, e.g. azelastine, pentylenetetrazole
A61P 33/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
33Antiparasitic agents
02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
CPC
A61P 33/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
33Antiparasitic agents
02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • TECHNISCHE UNIVERSITÄT CAROLO-WILHELMINA ZU BRAUNSCHWEIG [DE]/[DE] (AllExceptUS)
  • YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM [IL]/[IL] (AllExceptUS)
  • KUNICK, Conrad [DE]/[DE] (UsOnly)
  • REICHWALD, Christina [DE]/[DE] (UsOnly)
  • DUNKEL, Ute [DE]/[DE] (UsOnly)
  • JAFFE, Charles [IL]/[IL] (UsOnly)
  • SHIMONY, Orly [IL]/[IL] (UsOnly)
Inventors
  • KUNICK, Conrad
  • REICHWALD, Christina
  • DUNKEL, Ute
  • JAFFE, Charles
  • SHIMONY, Orly
Agents
  • KRÖNCKE, Rolf
Priority Data
60/950,39418.07.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PAULLONE DERIVATIVES AND ITS USE
(FR) DÉRIVÉS DE PAULLONE ET LEURS UTILISATION
Abstract
(EN)
The present invention relates to new paullone derivatives. In particular, the present invention relates to new paullone derivatives having anti-protozoan activity, in particular, anti-leishmanial activity. In a further aspect, the present invention relates to pharmaceutical compositions containing said paullones.
(FR)
La présente invention concerne de nouveaux dérivés de paullone. En particulier, la présente invention concerne de nouveaux dérivés de paullone ayant une activité anti-protozoaire, notamment, une activité anti-leishmaniale. Selon un autre aspect, la présente invention concerne des compositions pharmaceutiques contenant lesdits paullones.
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