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1. (WO2009009357) IMPLANTABLE MEDICAL DEVICES HAVING ADJUSTABLE PORE VOLUME AND METHODS FOR MAKING THE SAME
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2009/009357 International Application No.: PCT/US2008/068958
Publication Date: 15.01.2009 International Filing Date: 02.07.2008
IPC:
A61L 31/14 (2006.01) ,A61L 31/16 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
14
Materials characterised by their function or physical properties
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
L
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
31
Materials for other surgical articles
14
Materials characterised by their function or physical properties
16
Biologically active materials, e.g. therapeutic substances
Applicants:
BOSTON SCIENTIFIC SCIMED, INC. [US/US]; One SCIMED Place Maple Grove, Minnesota 55311-1566, US (AllExceptUS)
SHEU, Min-Shyan [US/US]; US (UsOnly)
WALAK, Steve [US/US]; US (UsOnly)
XU, Yixin [CN/US]; US (UsOnly)
Inventors:
SHEU, Min-Shyan; US
WALAK, Steve; US
XU, Yixin; US
Agent:
SHANLEY, Daniel, G.; Kenyon & Kenyon 1500 K Street, NW Suite 700 Washington, District Of Columbia 20005-1256, US
Priority Data:
60/948,25406.07.2007US
Title (EN) IMPLANTABLE MEDICAL DEVICES HAVING ADJUSTABLE PORE VOLUME AND METHODS FOR MAKING THE SAME
(FR) DISPOSITIFS MÉDICAUX IMPLANTABLES PERMETTANT D'AJUSTER LE VOLUME DES PORES ET LEURS PROCÉDÉS DE PRODUCTION
Abstract:
(EN) The present invention is directed to implantable medical devices which may be used for controllably releasing a therapeutic agent within a patient and methods for making the same. These medical devices may include porous coatings, which may be polymer- free, located on an outer surface or ab luminal surface of the medical device. The medical device may be a stent. The pores of the porous coating may be expandable to facilitate loading of the therapeutic agent. The medical device may be triggerable upon implantation of the medical device such that the volume of the voids shrinks to eject the therapeutic agent. The voids may be slots in the stent. Expandable materials or structures may be positioned in the voids to expand upon implantation and eject the therapeutic agent.
(FR) La présente invention concerne des dispositifs médicaux implantables qui peuvent être utilisés pour libérer de manière contrôlée un agent thérapeutique chez un patient, ainsi que les procédés de production correspondants. Ces dispositifs médicaux peuvent comprendre des revêtements poreux, qui peuvent être dépourvus de polymères, situés sur une surface externe ou abluminale du dispositif médical. Le dispositif médical peut être un stent. Les pores du revêtement poreux peuvent se dilater afin de faciliter l'incorporation de l'agent thérapeutique. Le dispositif médical peut s'actionner lors de son implantation, ce qui permet de réduire le volume des espaces vides et expulser l'agent thérapeutique. Les espaces vides peuvent correspondre aux fentes présentes sur le stent. Des matériaux ou des structures susceptibles de se dilater peuvent être disposés dans les espaces vides afin de se dilater lors de l'implantation et expulser l'agent thérapeutique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
EP2173400JP2010532701EP2404628