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1. WO2009005559 - LUNG FLUID STATUS MONITORING

Publication Number WO/2009/005559
Publication Date 08.01.2009
International Application No. PCT/US2008/004914
International Filing Date 16.04.2008
IPC
A61B 5/053 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
05Measuring for diagnosis by means of electric currents or magnetic fields
053Measuring electrical impedance or conductance of a portion of the body
A61B 5/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
08Measuring devices for evaluating the respiratory organs
A61N 1/37 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
362Heart stimulators
37Monitoring; Protecting
A61N 1/365 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
362Heart stimulators
365controlled by a physiological parameter, e.g. by heart potential
A61N 1/362 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
362Heart stimulators
CPC
A61B 2560/0468
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
04Constructional details of apparatus
0462Apparatus with built-in sensors
0468Built-in electrodes
A61B 5/0031
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
0031Implanted circuitry
A61B 5/0537
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
053Measuring electrical impedance or conductance of a portion of the body
0537Measuring body composition by impedance, e.g. tissue hydration or fat content
A61B 5/0538
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
053Measuring electrical impedance or conductance of a portion of the body
0538invasively, e.g. using a catheter
A61B 5/0809
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
0809by impedance pneumography
A61B 5/087
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
08Detecting, measuring or recording devices for evaluating the respiratory organs
087Measuring breath flow
Applicants
  • CARDIAC PACEMAKERS, INC. [US]/[US] (AllExceptUS)
  • BELALCAZAR, Andres [CO]/[US] (UsOnly)
  • LEWICKE, Aaron [US]/[US] (UsOnly)
Inventors
  • BELALCAZAR, Andres
  • LEWICKE, Aaron
Agents
  • STEFFEY, Charles E.
Priority Data
11/772,35202.07.2007US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LUNG FLUID STATUS MONITORING
(FR) SURVEILLANCE DU STATUT D'UN LIQUIDE PULMONAIRE
Abstract
(EN)
Systems and methods for monitoring lung fluid status, such as monitoring the presence or absence of pulmonary edema, in a subject using information about the cardiac impedance-indicating component of a measured impedance-indicating signal. In various examples, an amplitude or contribution change over multiple cardiac cycles of the cardiac impedance-indicating component is used to compute and provide a lung status indication. In various examples, a decreasing amplitude or contribution trend of the cardiac impedance-indicating component signifies an increasing amount of fluid in the subject's lungs, as a greater portion of an injected thoracic impedance measurement current formerly traversing the heart is rerouted through the lung due to the less resistance path created by the fluid accumulation therein. In another example, measurements of the impedance-indicating signal, and thus the cardiac impendence-indicating component, are taken at one or a combination of end-inspiration or end-expiration.
(FR)
L'invention concerne des systèmes et des procédés pour surveiller le statut d'un liquide pulmonaire, comme la surveillance de la présence ou de l'absence d'un œdème pulmonaire, chez un sujet en utilisant une information sur un composant, indicateur d'impédance cardiaque, d'un signal, indicateur d'impédance, mesuré. Dans divers exemples, un changement d'amplitude ou de contribution sur des cycles cardiaques multiples du composant indicateur d'impédance cardiaque est utilisé pour calculer et fournir une indication sur le statut pulmonaire. Dans divers exemples, une tendance, décroissante d'amplitude, ou de contribution du composant indicateur d'impédance cardiaque signifie une quantité croissante de liquide dans les poumons du sujet, du fait qu'une grande partie d'un courant de mesure d'impédance thoracique injecté traversant auparavant le cœur est redirigée à travers le poumon en raison du passage de moindre résistance créé par l'accumulation de liquide à l'intérieur. Dans un autre exemple, les mesures du signal indicateur d'impédance, et donc du composant indicateur d'impédance cardiaque, sont effectuées au moment d'une inspiration finale ou d'une expiration finale, ou lors d'une combinaison de celles-ci.
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