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1. WO2009004188 - DIRECT DISSOLUTION OF DOCETAXEL IN A SOLVENT IN POLYSORBATE 80

Publication Number WO/2009/004188
Publication Date 08.01.2009
International Application No. PCT/FR2008/000766
International Filing Date 06.06.2008
IPC
A61K 31/337 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
CPC
A61K 31/337
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
337having four-membered rings, e.g. taxol
A61K 9/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
08Solutions
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 305/14
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
305Heterocyclic compounds containing four-membered rings having one oxygen atoms as the only ring hetero atoms
14condensed with carbocyclic rings or ring systems
Applicants
  • AVENTIS PHARMA S.A. [FR]/[FR] (AllExceptUS)
  • AUTHELIN, Jean-René [FR]/[FR] (UsOnly)
  • DIDIER, Eric [FR]/[FR] (UsOnly)
  • FOUQUE, Elie [FR]/[FR] (UsOnly)
  • NAKACH, Mostafa [FR]/[FR] (UsOnly)
Inventors
  • AUTHELIN, Jean-René
  • DIDIER, Eric
  • FOUQUE, Elie
  • NAKACH, Mostafa
Agents
  • LE PENNEC, Magali
Priority Data
070409508.06.2007FR
Publication Language French (FR)
Filing Language French (FR)
Designated States
Title
(EN) DIRECT DISSOLUTION OF DOCETAXEL IN A SOLVENT IN POLYSORBATE 80
(FR) DISSOLUTION DIRECTE DU DOCETAXEL DANS UN SOLVANT DANS LE POLY SORBATE 80
Abstract
(EN)
The invention relates to the solubilisation of docetaxel in an organic solvent, to the mixture thereof with polysorbate 80 and to the evaporation of the solvent.
(FR)
Elle concerne la solubilisation du docétaxel dans un solvant organique, son mélange avec le polysorbate 80 et l' évaporation du solvant.
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