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1. (WO2008121301) CRYSTALLINE ANTI-HUMAN IL-12 ANTIBODIES

Pub. No.:    WO/2008/121301    International Application No.:    PCT/US2008/004006
Publication Date: Fri Oct 10 01:59:59 CEST 2008 International Filing Date: Fri Mar 28 00:59:59 CET 2008
IPC: C07K 16/00
C12P 21/08
Applicants: ABBOTT LABORATORIES
BORHANI, David W.
FRAUNHOFER, Wolfgang
KRAUSE, Hans-Juergen
KOENIGSDORFER, Anette
WINTER, Gerhard
GOTTSCHALK, Stefan
Inventors: BORHANI, David W.
FRAUNHOFER, Wolfgang
KRAUSE, Hans-Juergen
KOENIGSDORFER, Anette
WINTER, Gerhard
GOTTSCHALK, Stefan
Title: CRYSTALLINE ANTI-HUMAN IL-12 ANTIBODIES
Abstract:
The invention relates to batch crystallization methods for crystallizing an anti-hIL-12 antibody that allows the production of the antibody on an industrial scale, antibody crystals obtained according to the methods, compositions containing the crystals, and methods of using the crystals and the compositions.