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1. (WO2008103500) THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/103500    International Application No.:    PCT/US2008/050434
Publication Date: 28.08.2008 International Filing Date: 07.01.2008
IPC:
C07D 417/10 (2006.01), C07D 417/14 (2006.01), A61K 31/427 (2006.01), A61P 3/10 (2006.01)
Applicants: IRM LLC [US/US]; 131 Front Street,, P.O. Box HM 2899,, Hamilton HM LX (BM) (For All Designated States Except US).
EPPLE, Robert [AT/US]; (US) (For US Only).
AZIMIOARA, Mihai [US/US]; (US) (For US Only).
COW, Christopher [CA/US]; (US) (For US Only).
RUSSO, Ross [US/US]; (US) (For US Only).
NIKULIN, Victor [RU/US]; (US) (For US Only).
LELAIS, Gerald [CH/US]; (US) (For US Only)
Inventors: EPPLE, Robert; (US).
AZIMIOARA, Mihai; (US).
COW, Christopher; (US).
RUSSO, Ross; (US).
NIKULIN, Victor; (US).
LELAIS, Gerald; (US)
Agent: TONGCO WU, Emily; Genomics Institute of the Novartis Research Foundation, 10675 John Jay Hopkins Drive, San Diego, California 92121 (US)
Priority Data:
60/891,184 22.02.2007 US
Title (EN) THIAZOLE DERIVATIVES AS MODULATORS OF G PROTEIN-COUPLED RECEPTORS
(FR) DÉRIVÉS DE THIAZOLE EN TANT QUE MODULATEURS DE RÉCEPTEURS COUPLÉS AUX PROTÉINES G
Abstract: front page image
(EN)The invention provides compounds of formula (IA) or (IB) and pharmaceutical compositions thereof, which are useful for modulating G protein-coupled receptor 120 (GPR120), and methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated GPR120.
(FR)L'invention concerne des composés de la formule (IA) ou (IB) et leurs compositions pharmaceutiques, qui sont utiles pour moduler un récepteur 120 couplé aux protéines G (GPR120), et des procédés pour utiliser de tels composés pour traiter, améliorer ou prévenir une affection associée à un GPR120 anormal ou dérégulé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)