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1. (WO2008103277) NITROGEN-CONTAINING HETEROCYCLYL KETONES AND THEIR USE AS C-MET INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/103277    International Application No.:    PCT/US2008/002007
Publication Date: 28.08.2008 International Filing Date: 15.02.2008
IPC:
C07D 237/16 (2006.01), A61K 31/4709 (2006.01), A61K 31/4545 (2006.01), A61K 31/444 (2006.01), A61K 31/501 (2006.01), A61K 31/497 (2006.01), C07D 401/06 (2006.01), C07D 401/12 (2006.01), C07D 401/14 (2006.01), C07D 405/14 (2006.01), C07D 409/14 (2006.01), C07D 417/14 (2006.01), C07D 471/04 (2006.01)
Applicants: AMGEN INC. [US/US]; One Amgen Center Drive, Thousand Oaks, California 91320-1799 (US) (For All Designated States Except US).
ALBRECHT, Brian K. [US/US]; (US) (For US Only).
BELLON, Steven [US/US]; (US) (For US Only).
BOOKER, Shon [US/US]; (US) (For US Only).
CHENG, Alan C. [US/US]; (US) (For US Only).
D'AMICO, Derin [US/US]; (US) (For US Only).
D'ANGELO, Noel [US/US]; (US) (For US Only).
HARMANGE, Jean-christophe [FR/US]; (US) (For US Only).
KIM, Tae-seong [US/US]; (US) (For US Only).
LIU, Longbin [US/US]; (US) (For US Only).
NORMAN, Mark H. [US/US]; (US) (For US Only).
SIEGMUND, Aaron C. [US/US]; (US) (For US Only).
STEC, Markian [US/US]; (US) (For US Only).
XI, Ning [CN/US]; (US) (For US Only).
YANG, Kevin [US/US]; (US) (For US Only)
Inventors: ALBRECHT, Brian K.; (US).
BELLON, Steven; (US).
BOOKER, Shon; (US).
CHENG, Alan C.; (US).
D'AMICO, Derin; (US).
D'ANGELO, Noel; (US).
HARMANGE, Jean-christophe; (US).
KIM, Tae-seong; (US).
LIU, Longbin; (US).
NORMAN, Mark H.; (US).
SIEGMUND, Aaron C.; (US).
STEC, Markian; (US).
XI, Ning; (US).
YANG, Kevin; (US)
Agent: HERMENAU, Ronald S.; 1120 Veterans Boulevard, ASF1-1, South San Francisco, California 94080 (US)
Priority Data:
60/902,030 16.02.2007 US
Title (EN) NITROGEN-CONTAINING HETEROCYCLYL KETONES AND THEIR USE AS C-MET INHIBITORS
(FR) CÉTONES D'HÉTÉROCYCLYLE CONTENANT DE L'AZOTE ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)Selected compounds defined by Formula I, II, III, IV or V are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases.
(FR)L'invention concerne des composés sélectionnés efficaces dans la prophylaxie et le traitement de maladies, par exemple des maladies médiées par HGF. L'invention concerne de nouveaux composés, analogues, promédicaments et sels acceptables d'un point de vue pharmaceutique de ceux-ci, des compositions pharmaceutiques et des méthodes prophylactiques et thérapeutiques utilisées dans des maladies ou des états pathologiques tels que le cancer et analogues. L'invention concerne également des procédés de fabrication desdits composés, ainsi que des intermédiaires utilisés dans lesdits procédés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)