WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |

Search International and National Patent Collections
World Intellectual Property Organization
Machine translation
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/103146    International Application No.:    PCT/US2007/004899
Publication Date: 28.08.2008 International Filing Date: 23.02.2007
C12N 9/72 (2006.01), A61K 38/00 (2006.01)
Applicants: LANDING BIOTECH, INC. [US/US]; 60 Grove Street, Suite 1A, Auburndale, Massachusetts 02466 (US) (For All Designated States Except US).
LIU, Jian-ning [CN/US]; (US) (For US Only)
Inventors: LIU, Jian-ning; (US)
Agent: GARCIA, Todd E.; Fish & Richardson P.C., P.O. Box 1022, Minneapolis, Minnesota 55440-1022 (US)
Priority Data:
Abstract: front page image
(EN)The present application features methods and compositions for treating patients suffering from atherosclerosis or at risk for developing atherosclerosis. The treatment includes administering to the patient a pharmaceutical composition that includes an agent capable of blocking the interaction between uPA and its receptor uPAR, e.g., an ATF or a fragment thereof, an anti-uPA antibody, a uPAR or a fragment thereof, or an antibody that specifically binds to uPAR.
(FR)La présente invention concerne des procédés et des compositions permettant de traiter des patients souffrant d'athérosclérose ou susceptibles de développer une athérosclérose. Le traitement comprend l'administration au patient d'une composition pharmaceutique qui comprend un agent capable de bloquer l'interaction entre uPA et son récepteur uPAR, par exemple un fragment amino-terminal (ATF) ou un fragment de celui-ci, un anticorps anti-uPA, un uPAR ou un fragment de celui-ci, ou un anticorps qui se lie spécifiquement à uPAR.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MD, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)