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1. (WO2008102937) MESENCHYMAL STEM CELL-MEDIATED AUTOLOGOUS DENDRITIC CELLS WITH INCREASED IMMUNOSUPPRESSION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102937    International Application No.:    PCT/KR2007/003681
Publication Date: 28.08.2008 International Filing Date: 31.07.2007
IPC:
C12N 5/00 (2006.01), C12N 5/0784 (2010.01), A61P 37/02 (2006.01)
Applicants: CREAGENE INC. [KR/KR]; 2F Joongang Induspia V B/D, 138-6 Samgdaewon-dong, Joongwon-gu, Sungnam-Si, Kyungki-do 426-713 (KR) (For All Designated States Except US).
LIM, Dae Seog [KR/KR]; (KR) (For US Only).
JEONG, Ju Ah [KR/KR]; (KR) (For US Only).
KANG, Mi-Sun [KR/KR]; (KR) (For US Only).
LEE, Hyun Soo [KR/KR]; (KR) (For US Only).
BAE, Yong Soo [KR/KR]; (KR) (For US Only)
Inventors: LIM, Dae Seog; (KR).
JEONG, Ju Ah; (KR).
KANG, Mi-Sun; (KR).
LEE, Hyun Soo; (KR).
BAE, Yong Soo; (KR)
Agent: YANG, Boo-Hyun; 4th Fl. Oksan Bldg., 1627-10, Bongcheon-7-dong, Gwanak-gu, Seoul 151-818 (KR)
Priority Data:
10-2007-0017970 22.02.2007 KR
Title (EN) MESENCHYMAL STEM CELL-MEDIATED AUTOLOGOUS DENDRITIC CELLS WITH INCREASED IMMUNOSUPPRESSION
(FR) CELLULES DENDRITIQUES OTOLOGUES INDUITES PAR CELLULES SOUCHES MÉSENCHYMATEUSES À IMMUNOSUPPRESSION ACCRUE
Abstract: front page image
(EN)The present invention relates to a method for preparing dendritic cells which have an enhanced potential to suppress immune responses, dendritic cells carrying a potential to suppress immune responses, and a pharmaceutical composition comprising the dendritic cells capable of inducing immunosuppressive responses. The present dendritic cells having an enhanced potential to suppress immune responses can be utilized for treating various diseases or disorders through the suppression of immune responses. In addition, the enhanced immunotolerance potential of the dendritic cells of this invention ensures the cells to be effectively used as an immunosuppressive agent.
(FR)La présente invention concerne un procédé de préparation de cellules dendritiques qui possèdent un potentiel renforcé pour supprimer des réponses immunes, des cellules dendritiques porteuses d'un potentiel pour supprimer des réponses immunes, et une composition pharmaceutique comprenant ces cellules dendritiques capables d'induire des réponses immunosuppressives. Ces cellules dendritiques possédant un potentiel renforcé pour supprimer des réponses immunes peuvent être utilisées pour traiter diverses maladies ou divers troubles par la suppression de réponses immunes. Par ailleurs, le potentiel d'immunotolérance renforcé de ces cellules dendritiques permet à ces cellules d'être efficacement utilisées comme agent immunosuppresseur.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)