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1. (WO2008102572) METHOD FOR PRODUCTION OF L-AMINO ACID OR NUCLEIC ACID
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102572    International Application No.:    PCT/JP2008/050135
Publication Date: 28.08.2008 International Filing Date: 09.01.2008
IPC:
C12P 13/04 (2006.01), C12P 19/28 (2006.01), C12P 19/30 (2006.01), C12P 19/38 (2006.01)
Applicants: AJINOMOTO CO., INC. [JP/JP]; 15-1, Kyobashi 1-chome, Chuo-ku, Tokyo 1048315 (JP) (For All Designated States Except US).
ARAKI, Masayuki [JP/JP]; (JP) (For US Only).
TAKAHASHI, Yusuke [JP/JP]; (JP) (For US Only).
WATANABE, Akihiro [JP/JP]; (JP) (For US Only).
OHNISHI, Fumito [JP/JP]; (JP) (For US Only).
ASANO, Takahiro [JP/JP]; (JP) (For US Only).
KONDO, Kazuya [JP/JP]; (JP) (For US Only).
HIBINO, Wataru [JP/JP]; (JP) (For US Only).
IWATANI, Shintaro [JP/JP]; (JP) (For US Only).
OKUTANI, Satoshi [JP/JP]; (JP) (For US Only)
Inventors: ARAKI, Masayuki; (JP).
TAKAHASHI, Yusuke; (JP).
WATANABE, Akihiro; (JP).
OHNISHI, Fumito; (JP).
ASANO, Takahiro; (JP).
KONDO, Kazuya; (JP).
HIBINO, Wataru; (JP).
IWATANI, Shintaro; (JP).
OKUTANI, Satoshi; (JP)
Agent: KAWAGUCHI, Yoshiyuki; Acropolis 21 Building 6th floor 4-10, Higashi Nihonbashi 3-chome Chuo-ku, Tokyo 1030004 (JP)
Priority Data:
2007-039843 20.02.2007 JP
Title (EN) METHOD FOR PRODUCTION OF L-AMINO ACID OR NUCLEIC ACID
(FR) PROCÉDÉ DE FABRICATION D'ACIDE AMINÉ L OU D'ACIDE NUCLÉIQUE
(JA) L-アミノ酸または核酸の製造方法
Abstract: front page image
(EN)Disclosed is a method for producing an L-amino acid or a nucleic acid, which comprises the steps of culturing a microorganism capable of producing the L-amino acid or the nucleic acid in a liquid culture medium in a fermentation tank equipped with a mixing impeller and optionally adding a seed crystal to the culture medium to produce and accumulate a crystal of the L-amino acid or the nucleic acid in the culture medium, and collecting the crystal of the L-amino acid or the nucleic acid from the culture, wherein the power density of the mixing impeller is adjusted to 2.4 kW/m3 or less after the crystal is precipitated or after the seed crystal is added.
(FR)L'invention porte sur un procédé de fabrication d'un acide aminé L ou d'un acide nucléique. Ce procédé comprend les étapes consistant à cultiver un microorganisme capable de produire l'acide aminé L ou l'acide nucléique dans un milieu de culture liquide dans un réservoir de fermentation équipé d'une pale de mélange et à ajouter facultativement un cristal d'ensemencement au milieu de culture pour produire et accumuler un cristal de l'acide aminé L ou de l'acide nucléique dans le milieu de culture, et à recueillir le cristal de l'acide aminé L ou de l'acide nucléique à partir de la culture, la densité de puissance de la pale de mélange étant ajustée à 2,4 kW/m3 ou moins après que le cristal a précipité ou après que le cristal d'ensemencement est ajouté.
(JA) L-アミノ酸又は核酸の生産能を有する微生物を攪拌翼を備えた発酵槽中の液体培地で培養し、必要に応じて種晶を培地に添加して当該培地中にL-アミノ酸または核酸の結晶を生成、蓄積させ、培養物からL-アミノ酸又は核酸の結晶を採取するL-アミノ酸又は核酸の製造法において、攪拌翼の動力密度を結晶析出後又は種晶添加後に2.4kW/m3以下に制御する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)