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1. (WO2008102379) STABLE SUSTAINED RELEASE FORMULATIONS OF FLUVASTATIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102379    International Application No.:    PCT/IS2008/000006
Publication Date: 28.08.2008 International Filing Date: 19.02.2008
IPC:
A61K 9/28 (2006.01), A61K 31/00 (2006.01)
Applicants: ACTAVIS GROUP PTC EHF. [IS/IS]; Reykjavikurvegi 76-78, IS-220 Hafnarfjordur (IS) (For All Designated States Except US).
JOHANNSSON, Fjalar [IS/IS]; (IS) (For US Only)
Inventors: JOHANNSSON, Fjalar; (IS)
Agent: ARNASON FAKTOR; Gudridarstig 2-4, IS-113 Reykjavik (IS)
Priority Data:
8612 19.02.2007 IS
Title (EN) STABLE SUSTAINED RELEASE FORMULATIONS OF FLUVASTATIN
(FR) FORMULATIONS STABLES DE FLUVASTATINE À LIBÉRATION PROLONGÉE
Abstract: front page image
(EN)The invention provides stable solid sustained release pharmaceutical formulations of fluvastatin, which formulation do not need to include a pH-stabilising agent. The formulations can preferably contain amorphous, micronised material. Sustained release formulations are disclosed with excellent dissolution profiles. Preferred formulations include formulations of fluvastatin sodium.
(FR)La présente invention concerne des formulations stables et solides de fluvastatine à libération prolongée. Ces formulations ne nécessitent aucun agent de stabilisation du pH et contiennent de préférence de la matière amorphe micronisée. Les formulations à libération prolongée présentent d'excellents profils de dissolution. Les formulations préférées renferment de la fluvastatine sodique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)