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1. (WO2008102375) A PROCESS FOR PREPARATION OF HIGHLY PURE ISOTRETINOIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102375    International Application No.:    PCT/IN2008/000099
Publication Date: 28.08.2008 International Filing Date: 20.02.2008
IPC:
C07C 403/20 (2006.01)
Applicants: IPCA LABORATORIES LIMITED [IN/IN]; 48, Kandivli Industrial Estate, Charkop, Kandivli (West), Mumbai 400 067, Maharashtra (IN) (For All Designated States Except US).
KUMAR, Ashok [IN/IN]; (IN) (For US Only).
SINGH, Dharmendra [IN/IN]; (IN) (For US Only).
MAHALE, Ganesh, Devidas [IN/IN]; (IN) (For US Only).
RANA, Ragnesh, Kumar [IN/IN]; (IN) (For US Only).
KHARADE, Mahesh [IN/IN]; (IN) (For US Only)
Inventors: KUMAR, Ashok; (IN).
SINGH, Dharmendra; (IN).
MAHALE, Ganesh, Devidas; (IN).
RANA, Ragnesh, Kumar; (IN).
KHARADE, Mahesh; (IN)
Agent: NAIR, Gopakumar, G.; Patent & Trademark Agent (Regd.), Gopakumar Nair Associates, Nair Baug, Akurli Road, Kandivli (East), Mumbai 400 101, Maharashtra (IN)
Priority Data:
315/MUM/2007 20.02.2007 IN
Title (EN) A PROCESS FOR PREPARATION OF HIGHLY PURE ISOTRETINOIN
(FR) PROCÉDÉ DE PRÉPARATION D'ISOTRÉTINOÏNE DE HAUTE PURETÉ
Abstract: front page image
(EN)Disclosed herein is a process for preparation of isotretinoin and more specifically, to a purification process for obtaining highly pure isotretinoin, by treating heavy metal and/or other impurities contaminated isotretinoin with a base in a solvent to obtain a solution; treating said solution with an adsorbent; and recovering isotretinoin substantially free from heavy metal & oxidized impurities.
(FR)L'invention porte sur un procédé de préparation d'isotrétinoïne et plus spécifiquement, d'isotrétinoïne de haute pureté, consistant à traiter de l'isotrétinoïne contaminée par des métaux lourds et/ou d'autres impuretés par une base dans un solvant pour obtenir une solution; à traiter ladite solution par un adsorbant; et à récupérer l'isotrétinoïne quasiment exempte de métaux lourds et d'impuretés oxydées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)