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Machine translation
1. (WO2008102161) CRYSTALLINE MINOCYCLINE BASE AND PROCESSES FOR ITS PREPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102161    International Application No.:    PCT/GB2008/000625
Publication Date: 28.08.2008 International Filing Date: 22.02.2008
Chapter 2 Demand Filed:    25.02.2009    
IPC:
C07C 237/26 (2006.01)
Applicants: HOVIONE INTER LTD. [CH/CH]; Bahnhofstrasse 21, CH-6000 Lucerne 7 (CH) (For All Designated States Except US).
MENDES, Zita [PT/PT]; (PT) (For US Only).
ANTUNES, Jose, Rafael [PT/PT]; (PT) (For US Only).
MARTO, Susana [PT/PT]; (PT) (For US Only).
HEGGIE, William [GB/PT]; (PT) (For US Only)
Inventors: MENDES, Zita; (PT).
ANTUNES, Jose, Rafael; (PT).
MARTO, Susana; (PT).
HEGGIE, William; (PT)
Agent: TURNER, Craig, R.; A.A. Thornton & Co. 235 High Holborn London WC1V 7LE (GB)
Priority Data:
103661 23.02.2007 PT
Title (EN) CRYSTALLINE MINOCYCLINE BASE AND PROCESSES FOR ITS PREPARATION
(FR) BASE DE MINOCYCLINE CRISTALLINE ET PROCÉDÉS DE PRÉPARATION
Abstract: front page image
(EN)The invention provides crystalline minocycline base. In particular, three crystalline polymorphic forms, designated Form I, Form Il and Form III, of minocycline base are provided. These are characterised by XRD and IR data. Processes for preparing the new polymorphic forms are also provided. For example, Form I is prepared by dissolving and/or suspending amorphous minocycline base in an organic solvent chosen from ethers followed by crystallisation from the mixture.
(FR)L'invention concerne une base de minocycline cristalline. L'invention concerne en particulier trois formes cristallines polymorphes, désignées sous le nom de forme I, forme Il et forme III, d'une base de minocycline. Celles-ci se caractérisent par des données XRD et IR. L'invention concerne également des procédés de préparation des nouvelles formes polymorphes. Par exemple, la forme I est préparée par dissolution et/ou suspension de la base de minocycline amorphe dans un solvant organique sélectionné parmi des éthers, puis par cristallisation du mélange.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)