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1. (WO2008102145) PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE MAGNESIUM DIHYDRATE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/102145    International Application No.:    PCT/GB2008/000602
Publication Date: 28.08.2008 International Filing Date: 21.02.2008
IPC:
C07D 401/12 (2006.01), A61K 31/4427 (2006.01), A61P 1/04 (2006.01)
Applicants: CIPLA LIMITED [IN/IN]; 289 Bellasis Road, Mumbai central, Mumbai 400 008, Maharashatra (IN) (For All Designated States Except US).
RAO, Dharmaraj, Ramachandra [IN/IN]; (IN) (For US Only).
KANKAN, Rajendra, Narayanrao [IN/IN]; (IN) (For US Only).
PATHI, Srinivas, Laxminarayan [IN/IN]; (IN) (For US Only).
BANGALORE, Gopalakrishna, Sumana [IN/IN]; (IN) (For US Only).
CURTIS, Philip, Anthony [GB/GB]; (GB) (MW only)
Inventors: RAO, Dharmaraj, Ramachandra; (IN).
KANKAN, Rajendra, Narayanrao; (IN).
PATHI, Srinivas, Laxminarayan; (IN).
BANGALORE, Gopalakrishna, Sumana; (IN)
Agent: COTTRILL, Emily, Elizabeth, Helen; A.A. Thornton & Co, 235 High Holborn, London WC1V 7LE (GB)
Priority Data:
348/MUM/2007 21.02.2007 IN
Title (EN) PROCESS FOR THE PREPARATION OF ESOMEPRAZOLE MAGNESIUM DIHYDRATE
(FR) PROCÉDÉ POUR LA PRÉPARATION DE ÉSOMÉPRAZOLE MAGNÉSIUM DIHYDRATÉ
Abstract: front page image
(EN)A process for preparing Form A of (S) -5-methoxy-2- [ [ (4-methoxy-3, 5-dimethyl-2-pyridinyl) - methyl] sulf inyl] -1 H-benzimidazole magnesium dihydrate, processes for preparing various intermediates useful in the preparation of Form A of (S) -5-methoxy-2- [ [ (4-methoxy-3, 5-dimethyl-2-pyridinyl) -methyl] sulf inyl] -1 H-benzimidazole magnesium dihydrate and a novel polymorphic Form II of 5-methoxy-2- [ [ (4-methoxy-3, 5-dimethyl-2-pyridinyl) -methyl] thio] -1 H-benzimidazole
(FR)La présente invention se rapporte à un procédé pour la préparation de la forme A de (S)-5-méthoxy-2-[[(4-méthoxy-3,5-diméthyl-2-pyridinyl)- méthyl]sulfinyl]-1 H-benzimidazole magnésium dihydraté, ainsi qu'à des procédés pour la préparation de divers intermédiaires utiles dans la préparation de la forme A de (S)-5-méthoxy-2-[[(4-méthoxy-3,5- diméthyl-2-pyridinyl)-méthyl]sulfinyl]-1 H-benzimidazole magnésium dihydraté et une nouvelle forme polymorphe II de 5-méthoxy-2-[[(4-méthoxy-3,5-diméthyl-2-pyridinyl)-méthyl]thio]-1 H- benzimidazole.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)