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Machine translation
1. (WO2008101936) CELLS FOR HEART TREATMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/101936    International Application No.:    PCT/EP2008/052027
Publication Date: 28.08.2008 International Filing Date: 20.02.2008
IPC:
A61K 35/00 (2006.01), C12N 5/077 (2010.01)
Applicants: CHARITÉ - UNIVERSITÄTSMEDIZIN BERLIN [DE/DE]; Charitéplatz 1, 10117 Berlin (DE) (For All Designated States Except US).
HAAG, Marion [DE/DE]; (DE) (For US Only).
RINGE, Jochen [DE/DE]; (DE) (For US Only).
SITTINGER, Michael [DE/DE]; (DE) (For US Only).
TSCHÖPE, Carsten [DE/DE]; (DE) (For US Only)
Inventors: HAAG, Marion; (DE).
RINGE, Jochen; (DE).
SITTINGER, Michael; (DE).
TSCHÖPE, Carsten; (DE)
Agent: BAUMGÄRTEL, Gunnar; Maikowski & Ninnemann, Postfach 15 09 20, 10671 Berlin (DE)
Priority Data:
10 2007 008 650.6 20.02.2007 DE
Title (DE) ZELLEN ZUR THERAPIE DES HERZENS
(EN) CELLS FOR HEART TREATMENT
(FR) CELLULES POUR LE TRAITEMENT CARDIAQUE
Abstract: front page image
(DE)Erfindungsgemäß werden fibroblastenartige, aus Herzmuskelbiopsien gewonnene Zellen, welche CD90-negativ, CD105-positiv, CD117-negativ und/oder CD166-positiv sind, sowie Zellzubereitungen solcher Zellen zur Therapie von Herzerkrankungen, sowie ein Verfahren zur Bereitstellung derselben offenbart. Die erfindungsgemäßen Zellen zeichnen sich gute Kultivierbarkeit in Zellkultur aus. Weiterhin wird ein Verfahren zur Gewinnung der erfindungsgemäßen Zellen und Zellzubereitungen offenbart.
(EN)The invention relates to fibroblast-type cells, obtained in myocardium biopsies, said cells being CD90 negative, CD105 positive, CD117 negative and/or CD166 positive, in addition to cell preparations of cells of this type for the treatment of cardiac disease. The invention also relates to a method for preparing said cells. The cells according to the invention exhibit good culturing properties in cell cultures. The invention further relates to a method for obtaining the cells and cell preparations according to the invention.
(FR)L'invention concerne des cellules de type fibroblastes, issues de biopsies du myocarde, qui sont CD90-négatives, CD105-positives, CD117-négatives et/ou CD166-positives, ainsi que des préparations cellulaires de telles cellules pour le traitement de maladies cardiaques, ainsi qu'un procédé de préparation. Les cellules selon l'invention sont caractérisées en ce qu'elles ont une bonne aptitude à être cultivées dans une culture cellulaire. L'invention concerne également un procédé d'acquisition des cellules et préparations cellulaires selon l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)