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Machine translation
1. (WO2008101700) BISPECIFIC FUSION PROTEIN HAVING THERAPEUTIC AND DIAGNOSTIC POTENTIAL
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/101700    International Application No.:    PCT/EP2008/001369
Publication Date: 28.08.2008 International Filing Date: 21.02.2008
IPC:
A61K 47/48 (2006.01), A61P 9/00 (2006.01)
Applicants: EBERHARD-KARLS-UNIVERSITAET TUEBINGEN [DE/DE]; Universitaetsklinikum, Geissweg 3, 72076 Tuebingen (DE) (For All Designated States Except US).
LANGER, Harald [DE/DE]; (DE) (For US Only).
GAWAZ, Meinrad [DE/DE]; (DE) (For US Only).
BUHRING, Hans-Jorg [DE/DE]; (DE) (For US Only).
SKUTELLA, Thomas [DE/DE]; (DE) (For US Only).
JUNG, Gundram [DE/DE]; (DE) (For US Only)
Inventors: LANGER, Harald; (DE).
GAWAZ, Meinrad; (DE).
BUHRING, Hans-Jorg; (DE).
SKUTELLA, Thomas; (DE).
JUNG, Gundram; (DE)
Agent: LAUFER, Gabriele; Witte, Weller & Partner, Postfach 105462, 70047 Stuttgart (DE)
Priority Data:
10 2007 010 306.0 22.02.2007 DE
Title (DE) BISPEZIFISCHES FUSIONSPROTEIN MIT THERAPEUTISCHEM UND DIAGNOSTISCHEM POTENZIAL
(EN) BISPECIFIC FUSION PROTEIN HAVING THERAPEUTIC AND DIAGNOSTIC POTENTIAL
(FR) PROTÉINE DE FUSION BISPÉCIIFIQUE ET PROTENTIEL DIAGNOSTIC
Abstract: front page image
(DE)Die vorliegende Erfindung betrifft ein bispezifisches Konstrukt mit einem ersten Polypeptid, das an Kollagen bindet, sowie einem zweiten Polypeptid, das an endotheliale Vorläuferzellen bindet. Ferner betrifft die vorliegende Erfindung die Verwendung dieses Fusionsproteins zur Herstellung einer pharmazeutischen Zusammensetzung zur Behandlung von Gefäß- und/oder Gewebeläsionen.
(EN)The invention relates to a bispecific construct comprising a first polypeptide that binds to collagen and a second polypeptide which binds to endothelial precursor cells. The invention further relates to the use of said fusion protein for producing a pharmaceutical composition used for treating vascular and/or tissue lesions.
(FR)La présente invention concerne un gène hybride bispécifique contenant un premier polypeptide qui se lie au collagène, et un deuxième polypeptide qui se lie aux cellules précurseur de cellules endothéliales. L'invention concerne également l'utilisation de la protéine de fusion pour la production d'une composition pharmaceutique aux fins de traitement de lésions de vaisseaux et/ou de tissus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)