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Machine translation
1. (WO2008101660) SPIROCYCLIC CYCLOHEXANE DERIVATIVES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/101660    International Application No.:    PCT/EP2008/001271
Publication Date: 28.08.2008 International Filing Date: 19.02.2008
Chapter 2 Demand Filed:    22.12.2008    
IPC:
C07D 471/10 (2006.01), C07D 495/10 (2006.01), C07D 491/107 (2006.01), A61K 31/407 (2006.01), A61P 25/00 (2006.01)
Applicants: GRÜNENTHAL GMBH [DE/DE]; Zieglerstrasse 6, 52078 Aachen (DE) (For All Designated States Except US).
SCHUNK, Stefan [DE/DE]; (DE) (For US Only).
SAUNDERS, Derek [GB/DE]; (DE) (For US Only).
HARLFINGER, Stephanie [DE/DE]; (DE) (For US Only).
STEUFMEHL, Sonja [DE/DE]; (DE) (For US Only)
Inventors: SCHUNK, Stefan; (DE).
SAUNDERS, Derek; (DE).
HARLFINGER, Stephanie; (DE).
STEUFMEHL, Sonja; (DE)
Priority Data:
10 2007 009 319.7 22.02.2007 DE
Title (DE) SPIROCYCLISCHE CYCLOHEXAN-DERIVATE
(EN) SPIROCYCLIC CYCLOHEXANE DERIVATIVES
(FR) DÉRIVÉS DE CYCLOHEXANE SPIROCYCLIQUES
Abstract: front page image
(DE)Die vorliegende Erfindung betrifft spirocyclische Cyclohexan-Derivate (I), Verfahren zu deren Herstellung, Arzneimittel enthaltend diese Verbindungen und die Verwendung von spirocyclischen Cyciohexan-Derivaten zur Herstellung von Arzneimitteln. R1 und R2 bilden einen Pyrrolidin- oder Azetidinring. Dadurch wird eine erhöhte metabolische Stabilität erreicht.
(EN)The present invention relates to spirocyclic cyclohexane derivatives of formula (I), methods for the production thereof, medicaments containing these compounds and the use of spirocyclic cyclohexane derivatives for producing medicaments. R1 and R2 form a pyrrolidine or an azetidine ring, which results in an increased metabolic stability.
(FR)L'invention concerne des dérivés de cyclohexane spirocycliques de formule (I), des procédés pour leur production, des médicaments contenant ces composés, ainsi que l'utilisation de dérivés de cyclohexane spirocycliques pour produire des médicaments. R1 et R2 forment un cycle pyrrolidine ou azétidine, ce qui entraîne une augmentation de la stabilité métabolique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: German (DE)
Filing Language: German (DE)