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1. (WO2008100816) ANTIBODY LIBRAY DISPLAY BY YEAST CELL PLASMA MEMBRANE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/100816    International Application No.:    PCT/US2008/053398
Publication Date: 21.08.2008 International Filing Date: 08.02.2008
IPC:
A61K 39/00 (2006.01), C12N 1/00 (2006.01)
Applicants: MEDIMMUNE, LLC [US/US]; One Medimmune Way, Gaithersburg, MD 20878 (US) (For All Designated States Except US).
WU, Herren [US/US]; (US) (For US Only).
GAO, Changshou [CN/US]; (US) (For US Only)
Inventors: WU, Herren; (US).
GAO, Changshou; (US)
Agent: KREPPEL, Lisa; Medimmune, Inc., One Medimmune Way, Gaithersburg, MD 20878 (US)
Priority Data:
60/889,019 09.02.2007 US
Title (EN) ANTIBODY LIBRAY DISPLAY BY YEAST CELL PLASMA MEMBRANE
(FR) PRÉSENTATION D'ANTICORPS
Abstract: front page image
(EN)The present invention relates to antibodies or antibody fragments that may be displayed on the extracellular surface of the plasma membrane when expressed in a host cell. The present invention provides libraries comprising a plurality of plasma membrane displayed antibodies and methods of screening the libraries for antibodies or antibody fragments with desired characteristics.
(FR)La présente invention concerne des anticorps ou des fragments d'anticorps qui peuvent être présentés sur la surface extracellulaire de la membrane plasmique lorsqu'ils sont exprimés dans une cellule hôte. Cette invention fait appel à des banques comprenant une pluralité d'anticorps présentés sur la membrane plasmique et concerne également des procédés de criblage des banques en vue de trouver des anticorps ou des fragments d'anticorps ayant les caractéristiques désirées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)