WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2008100620) BICYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/100620    International Application No.:    PCT/US2008/002110
Publication Date: 21.08.2008 International Filing Date: 15.02.2008
IPC:
C07D 471/04 (2006.01), A61K 31/437 (2006.01), A61P 29/00 (2006.01), A61P 35/00 (2006.01), A61P 37/00 (2006.01), A61P 37/08 (2006.01)
Applicants: SUNESIS PHARMACEUTICALS, INC. [US/US]; 341 Oyster Point Boulevard, South San Francisco, CA 94080 (US) (For All Designated States Except US).
ALLEN, Darin [US/US]; (US) (For US Only).
AMERIKS, Michael, K. [US/US]; (US) (For US Only).
AXE, Frank, U. [US/US]; (US) (For US Only).
BURDETT, Matthew [US/US]; (US) (For US Only).
CAI, Hui [US/US]; (US) (For US Only).
CHOONG, Ingrid [US/US]; (US) (For US Only).
EDWARDS, James, P. [US/US]; (US) (For US Only).
LEW, Willard [US/US]; (US) (For US Only).
MEDUNA, Steven, P. [US/US]; (US) (For US Only)
Inventors: ALLEN, Darin; (US).
AMERIKS, Michael, K.; (US).
AXE, Frank, U.; (US).
BURDETT, Matthew; (US).
CAI, Hui; (US).
CHOONG, Ingrid; (US).
EDWARDS, James, P.; (US).
LEW, Willard; (US).
MEDUNA, Steven, P.; (US)
Agent: FARSIOU, David, N.; Woodcock Washburn LLP, Cira Centre, 12th Floor, 2929 Arch Street, Philadelphia, PA 19104 (US)
Priority Data:
60/889,987 15.02.2007 US
12/031,597 14.02.2008 US
Title (EN) BICYCLIC AMINOPROPYL TETRAHYDRO-PYRAZOLO-PYRIDINE MODULATORS OF CATHEPSIN S
(FR) MODULATEURS DE LA CATHEPSINE S À LA TÉTRAHYDRO-PYRAZOLO-PYRIDINE AMINOPROPYLE BICYCLIQUES
Abstract: front page image
(EN)Bicyclic aminopropyl tetrahydro-pyrazolo-pyridine compounds are described, which are useful as cathepsin S modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by cathepsin S activity, such as psoriasis, pain, multiple sclerosis, atherosclerosis, and rheumatoid arthritis.
(FR)L'invention concerne des composés de tétrahydro-pyrazolo-pyridine aminopropyle bicycliques, qui sont utiles en tant que modulateurs de la cathepsine S. De tels composés peuvent être utilisés dans des compositions pharmaceutiques et des procédés pour le traitement de maladies, de troubles et d'états provoqués par l'activité de la cathepsine S, tels que le psoriasis, la douleur, la sclérose en plaques, l'athérosclérose, et l'arthrite rhumatoïde.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)