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1. (WO2008100563) COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/100563    International Application No.:    PCT/US2008/001948
Publication Date: 21.08.2008 International Filing Date: 14.02.2008
IPC:
A61K 39/395 (2006.01)
Applicants: ONCOMED PHARMACEUTICALS, INC. [US/US]; 800 Chesapeake Drive, Redwood City, CA 94063-4748 (US) (For All Designated States Except US).
GURNEY, Austin [US/US]; (US) (For US Only).
AXELROD, Fumiko [US/US]; (US) (For US Only)
Inventors: GURNEY, Austin; (US).
AXELROD, Fumiko; (US)
Agent: McCABE, Kevin, W.; Sterne, Kessler, Goldstein & Fox P.L.L.C., 1100 New York Avenue, N.W., Washington, DC 20005-3934 (US)
Priority Data:
60/889,857 14.02.2007 US
60/942,491 07.06.2007 US
Title (EN) COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER
(FR) COMPOSITIONS ET MÉTHODES POUR DIAGNOSTIQUER ET TRAITER LE CANCER
Abstract: front page image
(EN)Humanized antibodies that specifically binds to a non-ligand binding region of human Notch 1 are described. Also described are methods of treating cancer, the methods comprising administering a therapeutically effective amount of a humanized anti-Notch 1 antibody.
(FR)L'invention concerne des anticorps humanisés se fixant spécifiquement à une région non ligand du récepteur Notch 1 humain. Elle décrit également des méthodes pour traiter le cancer, ces méthodes comprenant l'administration d'une quantité thérapeutiquement efficace d'anticorps anti-Notch 1 humanisé.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)