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Machine translation
1. (WO2008100418) ZINC COMPLEXES OF NATURAL AMINO ACIDS FOR TREATING ELEVATED COPPER CAUSED TOXICITIES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/100418    International Application No.:    PCT/US2008/001674
Publication Date: 21.08.2008 International Filing Date: 08.02.2008
Chapter 2 Demand Filed:    20.08.2008    
IPC:
A61K 31/315 (2006.01)
Applicants: SSV THERAPEUTICS, INC. [US/US]; 3995 Holden Drive Ann Arbor, MI 48103 (US) (For All Designated States Except US).
GOEL, Om, P. [US/US]; (US) (For US Only)
Inventors: GOEL, Om, P.; (US)
Agent: KIMBLE, Karen, L.; Technology Law, PLLC, 3595 N. Sunset Way, Sanford, MI 48657 (US)
Priority Data:
11/707,329 17.02.2007 US
Title (EN) ZINC COMPLEXES OF NATURAL AMINO ACIDS FOR TREATING ELEVATED COPPER CAUSED TOXICITIES
(FR) COMPLEXES DE ZINC D'ACIDES AMINÉS NATURELS POUR LE TRAITEMENT DE TOXICITÉS PROVOQUÉES PAR UN CUIVRE ÉLEVÉ
Abstract: front page image
(EN)The present invention relates to formulations of zinc complexes of natural amino acids, especially L-arginine, L-lysine, L-ornithine, and other natural amino acids, in a molar ratio of about 1 :2 (metal :amino acid), and compositions thereof. These pharmaceutical compositions offer better tolerated and faster acting regimens than common zinc salts (i.e., acetate, sulfate, etc.) for long term maintenance therapy of diseases caused by abnormal elevated copper levels, such as in Wilson's disease, inflammatory and fibrotic diseases and Alzheimer's disease.
(FR)La présente invention concerne des formulations de complexes de zinc d'acides aminés naturels, spécialement la L-arginine, la L-lysine, la L-ornithine et d'autres acides aminés naturels, dans un rapport molaire d'environ 1/2 (métal/acide aminé) et des compositions de celles-ci. Ces compositions pharmaceutiques offrent des régimes d'action mieux tolérés et plus rapides que les sels de zinc courants (c'est-à-dire, acétate, sulfate, etc.) pour une thérapie avec un maintien à long terme de maladies provoquées par des taux élevés anormaux de cuivre, telles que la maladie de Wilson, des maladies inflammatoires et fibrotiques et la maladie d'Alzheimer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)