WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2008100344) FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/100344    International Application No.:    PCT/US2007/080734
Publication Date: 21.08.2008 International Filing Date: 08.10.2007
IPC:
C12Q 1/68 (2006.01)
Applicants: SIRIGEN INC. [US/US]; 5385 Hollister Avenue Suite 105 Santa Barbara, CA 93111 (US) (For All Designated States Except US).
GAYLORD, Brent, S. [US/US]; (US) (For US Only).
HONG, Janice, W. [US/US]; (US) (For US Only).
FU, Tsu-ju [CN/US]; (US) (For US Only).
SUN, Cheng, Jun [CN/US]; (US) (For US Only)
Inventors: GAYLORD, Brent, S.; (US).
HONG, Janice, W.; (US).
FU, Tsu-ju; (US).
SUN, Cheng, Jun; (US)
Agent: BACSI, Steven, G.; Wilson Sonsini Goodrich & Rosati, 650 Page Mill Road, Palo Alto, CA 94304-1050 (US)
Priority Data:
60/825,615 06.10.2006 US
Title (EN) FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION
(FR) PROCÉDÉS ET MATÉRIAUX FLUORESCENTS POUR L'AMPLIFICATION DIRIGÉE DE SIGNAUX EN PROVENANCE DE BIOMARQUEURS
Abstract: front page image
(EN)Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
(FR)La présente invention concerne des procédés et des compositions comprenant un multichromophore et/ou un complexe multichromophore permettant d'identifier une biomolécule cible. Une biomolécule détectrice, par exemple un anticorps, peut être liée par liaison covalente au multichromophore. En outre, un chromophore signal peut être lié par liaison covalente au multichromophore. Le dispositif est tel que le chromophore signal peut recevoir de l'énergie du multichromophore suite à l'excitation de ce dernier. Comme la biomolécule détectrice est capable d'interagir avec la biomolécule cible, le multichromophore et/ou le complexe multichromophore peut fournir des signaux de détection renforcés concernant une biomolécule cible.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)