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1. (WO2008099920) THERAPEUTIC AGENT FOR INTERSTITIAL PULMONARY DISEASE COMPRISING ANTI-HMGB-1 ANTIBODY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099920    International Application No.:    PCT/JP2008/052526
Publication Date: 21.08.2008 International Filing Date: 15.02.2008
IPC:
A61K 39/395 (2006.01), A61P 11/00 (2006.01)
Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION [JP/JP]; 10-1, Hakozaki 6-chome, Higashi-ku, Fukuoka-shi, Fukuoka 8128581 (JP) (For All Designated States Except US).
KAGOSHIMA UNIVERSITY [JP/JP]; 21-24, Korimoto 1-chome, Kagoshima-shi, Kagoshima 8908580 (JP) (For All Designated States Except US).
SHINO-TEST CORPORATION [JP/JP]; 56, Kanda Jinbo-cho 1-chome, Chiyoda-ku, Tokyo 1018410 (JP) (For All Designated States Except US).
KUWANO, Kazuyoshi [JP/JP]; (JP) (For US Only).
HAMADA, Naoki [JP/JP]; (JP) (For US Only).
MARUYAMA, Ikuro [JP/JP]; (JP) (For US Only).
YAMADA, Shingo [JP/JP]; (JP) (For US Only)
Inventors: KUWANO, Kazuyoshi; (JP).
HAMADA, Naoki; (JP).
MARUYAMA, Ikuro; (JP).
YAMADA, Shingo; (JP)
Agent: SHIMIZU, Hatsushi; Kantetsu Tsukuba Bldg. 6F 1-1-1, Oroshi-machi Tsuchiura-shi, Ibaraki 3000847 (JP)
Priority Data:
2007-034293 15.02.2007 JP
Title (EN) THERAPEUTIC AGENT FOR INTERSTITIAL PULMONARY DISEASE COMPRISING ANTI-HMGB-1 ANTIBODY
(FR) AGENT THÉRAPEUTIQUE POUR MALADIE PULMONAIRE INTERSTITIELLE COMPORTANT UN ANTICORPS ANTI-HMGB-1
(JA) 抗HMGB-1抗体を含む間質性肺疾患治療剤
Abstract: front page image
(EN)Disclosed is a means effective for the treatment of an interstitial pulmonary disease including interstitial pneumonia such as IPF. It is suggested that an antibody directed against HMGB-1 is effective for the treatment of fibroid lung. Thus, provided is a preparation for the treatment of an interstitial pulmonary disease, which comprises an anti-HMGB-1 antibody.
(FR)L'invention propose un moyen efficace pour le traitement d'une maladie pulmonaire interstitielle comprenant la pneumonie interstitielle telle que IPF. Il est suggéré qu'un anticorps dirigé contre la HMGB-1 est efficace pour le traitement du poumon fibreux. Ainsi, il est proposé une préparation pour le traitement d'une maladie pulmonaire interstitielle qui comporte un anticorps anti-HMGB-1.
(JA) 本発明は、IPF等の間質性肺炎を含む間質性肺疾患を治療するのに有効な手段を提供することを目的とする。本発明により、HMGB-1に対する抗体が肺線維症の治療に効果的であることが示唆された。そこで本発明は、抗HMGB-1抗体を含む間質性肺疾患を治療するための製剤を提供するものである。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)