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1. (WO2008099145) PYRAZOLE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099145    International Application No.:    PCT/GB2008/000454
Publication Date: 21.08.2008 International Filing Date: 11.02.2008
IPC:
A61K 31/415 (2006.01), C07D 231/14 (2006.01), C07D 231/18 (2006.01), C07D 403/06 (2006.01), C07D 405/12 (2006.01), A61P 3/00 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London, Greater London W1K 1LN (GB) (MG only).
PACKER, Martin, John [GB/GB]; (GB) (For US Only).
SCOTT, James, Stewart [GB/GB]; (GB) (For US Only).
STOCKER, Andrew [GB/GB]; (GB) (For US Only).
WHITTAMORE, Paul, Robert, Owen [GB/GB]; (GB) (For US Only)
Inventors: PACKER, Martin, John; (GB).
SCOTT, James, Stewart; (GB).
STOCKER, Andrew; (GB).
WHITTAMORE, Paul, Robert, Owen; (GB)
Agent: GLOBAL INTELLECTUAL PROPERTY; AstraZeneca AB, S-151 85 Södertälje (SE)
Priority Data:
60/889,336 12.02.2007 US
60/985,735 06.11.2007 US
Title (EN) PYRAZOLE DERIVATIVES AS 11-BETA-HSD1 INHIBITORS
(FR) DÉRIVÉS DU PYRAZOLE COMME INHIBITEUR DE 11-BÊTA-HSD1
Abstract: front page image
(EN)A compound of formula (I): and pharmaceutically -acceptable salts thereof wherein the variable groups are defined within; their use in the inhibition of 11βHSD1, processes for making them and pharmaceutical compositions comprising them are also described.
(FR)L'invention porte sur un composé représenté par la formule (I) et sur des sels pharmaceutiquement acceptables de celui-ci, les groupes variables étant définis présentement ; sur leur utilisation dans l'inhibition de 11βHSD1, sur des procédés pour leur fabrication et sur des compositions pharmaceutiques les comprenant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)