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1. (WO2008099091) USE OF IVABRADINE FOR OBTAINING DRUGS FOR TREATING ENDOTHELIAL DYSFUNCTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099091    International Application No.:    PCT/FR2008/000027
Publication Date: 21.08.2008 International Filing Date: 10.01.2008
IPC:
A61K 31/55 (2006.01), A61P 9/10 (2006.01), A61P 25/28 (2006.01)
Applicants: LES LABORATOIRES SERVIER [FR/FR]; 12, place de la Défense, F-92415 Courbevoie Cedex (FR) (For All Designated States Except US).
BENATAR, Vidal [FR/FR]; (FR) (For US Only).
LEREBOURS-PIGEONNIERE, Guy [FR/FR]; (FR) (For US Only).
TARDIF, Jean-claude [CA/CA]; (CA) (For US Only).
THORIN, Eric [CA/CA]; (CA) (For US Only).
RHEAUME, Eric [CA/CA]; (CA) (For US Only)
Inventors: BENATAR, Vidal; (FR).
LEREBOURS-PIGEONNIERE, Guy; (FR).
TARDIF, Jean-claude; (CA).
THORIN, Eric; (CA).
RHEAUME, Eric; (CA)
Agent: LES LABORATOIRES SERVIER; 12, Place de la Défense, F-92415 Courbevoie Cédex (FR)
Priority Data:
0700189 11.01.2007 FR
Title (EN) USE OF IVABRADINE FOR OBTAINING DRUGS FOR TREATING ENDOTHELIAL DYSFUNCTION
(FR) UTILISATION DE L'IVABRADINE POUR L'OBTENTION DE MEDICAMENTS DESTINES AU TRAITEMENT DE LA DYSFONCTION ENDOTHELIALE
Abstract: front page image
(EN)The invention relates to the use of ivabradine or 3-{3-[{[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-l,3,5-trien-7- yl]-methyl}-(methyl)-amino]-propyl}-7,8-dimethoxy-l,3,4,5-tetrahydro-2H-3-benzazepin- 2-one, of the addition salts thereof to a pharmaceutically acceptable acid, and of the hydrates thereof, in order to obtain a drug for treating endothelial dysfunction.
(FR)Utilisation de l'ivabradine ou 3-{3-[{[(7S)-3,4-diméthoxybicyclo[4.2.0]octa-1,3,5-trién-7-yl]-methyl}-(methyl)-amino]-propyl}-7,8-diméthoxy-1,3,4,5-tétrahydro-2H-3-benzazépin-2-one, de ses sels d'addition à un acide pharmaceutiquement acceptable et de leurs hydrates, pour l'obtention d'un médicament destiné au traitement de Ia dysfonction endothéliale.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)