WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2008099084) PARENTERAL PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099084    International Application No.:    PCT/FR2008/000015
Publication Date: 21.08.2008 International Filing Date: 04.01.2008
IPC:
A61K 9/107 (2006.01), A61K 38/13 (2006.01)
Applicants: PHYSICA PHARMA [FR/FR]; Château Bersol - Bât. 2 218/228, avenue du Haut-Lévêque F-33600 Pessac (FR) (For All Designated States Except US).
BROUSSAUD, Olivier [FR/FR]; (FR) (For US Only).
POUGNAS, Jean-Luc [FR/FR]; (FR) (For US Only).
CALVET, Nicolas [FR/FR]; (FR) (For US Only)
Inventors: BROUSSAUD, Olivier; (FR).
POUGNAS, Jean-Luc; (FR).
CALVET, Nicolas; (FR)
Agent: CABINET ORES; BOLINCHES Michel, 36, rue de St Pétersbourg, F-75008 Paris (FR)
Priority Data:
0700127 09.01.2007 FR
Title (EN) PARENTERAL PHARMACEUTICAL COMPOSITION AND METHOD FOR PREPARING THE SAME
(FR) COMPOSITION PHARMACEUTIQUE PARENTÉRALE ET SON PROCEDE DE PREPARATION.
Abstract: front page image
(EN)The invention relates to a pharmaceutical composition in the form of an aqueous emulsion that contains a water low-solubility active ingredient, except for Propofol, and that can be essentially administered by intravenous injection, and to a method for preparing said composition. The invention more particularly relates to parenteral administrations of said composition, e.g. by cutaneous application. The pharmaceutical composition of the invention, which can be administered by intravenous injection, includes a solubilising system of said active ingredient comprising a combination of at least one pharmaceutically acceptable monovalent metallic salt of a fatty acid including 5 to 23 carbon atoms, such as sodium oleate, and at least one polyethylene glycol hydroxystearate such as PEG-15 hydroxystearate.
(FR)La présente invention conceme une composition pharmaceutique sous forme d'émulsion aqueuse qui comprend un principe actif peu soluble dans I'eau, a I'exclusion du Propofol, et qui est notamment apte à être administrée par injection intraveineuse, et un procédé pour Ia préparation de cette composition. L'invention s'applique de manière plus générale a des administrations parentérales de cette composition, par exemple par application cutanée. La composition pharmaceutique selon l'invention, qui est apte à être administrée par injection intraveineuse, comprend un système solubilisant de ce principe actif comprenant en combinaison au moins un sel métalliqueυe monovalent pharmaceutiquement acceptable d'un acide gras ayant de 5 à 23 atomes de carbone, tel que L'oléate de sodium, et au moins un polyéthylène glycol hydroxystearate, tel que Ie PEG-15 hydroxystearate.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)