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1. (WO2008099022) 10-SULFONYL-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099022    International Application No.:    PCT/EP2008/051905
Publication Date: 21.08.2008 International Filing Date: 15.02.2008
IPC:
C07D 243/38 (2006.01), C07D 471/04 (2006.01), C07D 401/12 (2006.01), C07D 403/12 (2006.01), C07D 413/12 (2006.01), C07D 495/04 (2006.01), C07D 513/04 (2006.01), A61K 31/5513 (2006.01), A61P 31/12 (2006.01)
Applicants: TIBOTEC PHARMACEUTICALS LTD. [IE/IE]; Eastgate Village, Eastgate, Little Island, Co Cork (IE) (For All Designated States Except US).
RABOISSON, Pierre Jean-Marie Bernard [FR/BE]; (BE) (For US Only).
VENDEVILLE, Sandrine Marie Helene [FR/BE]; (BE) (For US Only).
BONFANTI, Jean-François [FR/FR]; (FR) (For US Only).
MC GOWAN, David [US/BE]; (BE) (For US Only).
VANDYCK, Koen [BE/BE]; (BE) (For US Only).
DOUBLET, Frédéric Marc Maurice [FR/FR]; (FR) (For US Only).
HU, Lili [NL/BE]; (BE) (For US Only).
NYANGUILE, Origène [CH/BE]; (BE) (For US Only)
Inventors: RABOISSON, Pierre Jean-Marie Bernard; (BE).
VENDEVILLE, Sandrine Marie Helene; (BE).
BONFANTI, Jean-François; (FR).
MC GOWAN, David; (BE).
VANDYCK, Koen; (BE).
DOUBLET, Frédéric Marc Maurice; (FR).
HU, Lili; (BE).
NYANGUILE, Origène; (BE)
Agent: DAELEMANS, Frank; Tibotec-Virco Comm. VA, J & J Patent Law Department, Generaal De Wittelaan L 11B 3, B-2800 Mechelen (BE)
Priority Data:
07102526.6 16.02.2007 EP
Title (EN) 10-SULFONYL-DIBENZODIAZEPINONES USEFUL AS HEPATITIS C VIRUS INHIBITORS
(FR) 10-SULFONYL-DIBENZODIAZÉPINONES UTILES COMME INHIBITEURS DU VIRUS DE L'HÉPATITE C
Abstract: front page image
(EN)Inhibitors of HCV replication of formula (I) and the stereoisomers, prodrugs, tautomers, racemics, salts, hydrates or solvates thereof, wherein X, Y, R1; R2; R3; R4a and R4b have the meaning defined in the claims. The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.
(FR)L'invention porte sur des inhibiteurs de réplication du VHC de formule (I) et les stéréoisomères, les promédicaments, les tautomères, les racémiques, les sels, les hydrates ou les solvates de ceux-ci. Dans la formule, X, Y, R1 ; R2 ; R3 ; R4a et R4b ont la signification définie dans les revendications. La présente invention porte également sur des procédés de préparation desdits composés, sur des compositions pharmaceutiques les contenant et sur leur utilisation en thérapie du VHC.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)