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Machine translation
1. (WO2008099000) SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/099000    International Application No.:    PCT/EP2008/051824
Publication Date: 21.08.2008 International Filing Date: 15.02.2008
IPC:
C07D 209/04 (2006.01), C07D 401/04 (2006.01), C07D 401/14 (2006.01), C07D 403/04 (2006.01), C07D 403/14 (2006.01), A61K 31/404 (2006.01), A61K 31/416 (2006.01), A61P 3/10 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Str. 173, 55216 Ingelheim Am Rhein (DE) (For All Designated States Except US).
WAGNER, Holger [DE/DE]; (DE) (For US Only).
LANGKOPF, Elke [DE/DE]; (DE) (For US Only).
STREICHER, Ruediger [DE/DE]; (DE) (For US Only).
ECKHARDT, Matthias [DE/DE]; (DE) (For US Only).
SCHULER-METZ, Annette [DE/DE]; (DE) (For US Only).
PAUTSCH, Alexander [DE/DE]; (DE) (For US Only).
SCHOELCH, Corinna [DE/DE]; (DE) (For US Only)
Inventors: WAGNER, Holger; (DE).
LANGKOPF, Elke; (DE).
STREICHER, Ruediger; (DE).
ECKHARDT, Matthias; (DE).
SCHULER-METZ, Annette; (DE).
PAUTSCH, Alexander; (DE).
SCHOELCH, Corinna; (DE)
Agent: HAMMANN, Heinz; BOEHRINGER INGELHEIM GMBH, Binger Str. 173, 55216 Ingelheim am Rhein (DE)
Priority Data:
10 2007 007 751.5 16.02.2007 DE
Title (EN) SUBSTITUTED ARYLSULPHONYLGLYCINES, THE PREPARATION THEREOF AND THE USE THEREOF AS PHARMACEUTICAL COMPOSITIONS
(FR) NOUVELLES ARYLSULPHONYLGLYCINES SUBSTITUÉES, LEUR PROCÉDÉ DE PRÉPARATION ET LEUR UTILISATION EN TANT QUE COMPOSITIONS PHARMACEUTIQUES
Abstract: front page image
(EN)The present invention relates to substituted arylsulphonylglycines of general formula wherein R, R4, X, Y, Z and m are defined as in claim 1, the tautomers, enantiomers, diastereomers, mixtures thereof and salts thereof, which have valuable pharmacological properties, particularly the suppression of the interaction of glycogen phosphorylase a with the GL subunit of glycogen- associated protein phosphatase 1 (PP1 ), and their use as pharmaceutical compositions.
(FR)La présente invention concerne des arylsulphonylglycines substituées de formule générale (I), dans laquelle: R, R4, X, Y, Z et m sont tels que définis dans la revendication 1, leurs tautomères, énantiomères, diastéréoisomères, des mélanges de ceux-ci ainsi que leurs sels, ayant de précieuses propriétés pharmacologiques, notamment la suppression de l'interaction de la glycogène phosphorylase avec la sous-unité GL de la protéine phosphatase 1 associée (PP1), et leur utilisation en tant que compositions pharmaceutiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)