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1. (WO2008098178) TREATMENT OF RESISTANT OR REFRACTORY CANCERS WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/098178    International Application No.:    PCT/US2008/053438
Publication Date: 14.08.2008 International Filing Date: 08.02.2008
IPC:
A61K 31/33 (2006.01)
Applicants: ENZON PHARMACEUTICALS, INC. [US/US]; 685 Route 202/206, Bridgewater, NJ 08807 (US) (For All Designated States Except US).
ZHAO, Hong [US/US]; (US) (For US Only).
SAPRA, Puja [IN/US]; (US) (For US Only)
Inventors: ZHAO, Hong; (US).
SAPRA, Puja; (US)
Agent: MERCANTI, Michael N.; Lucas & Mercanti, LLP, 475 Park Avenue South, New York, NY 10016 (US)
Priority Data:
60/900,592 09.02.2007 US
Title (EN) TREATMENT OF RESISTANT OR REFRACTORY CANCERS WITH MULTI-ARM POLYMERIC CONJUGATES OF 7-ETHYL-10-HYDROXYCAMPTOTHECIN
(FR) TRAITEMENT DE CANCERS RÉSISTANTS OU RÉFRACTAIRES AVEC DES CONJUGUÉS POLYMÈRES MULTIBRINS DE 7-ÉTHYL-10-HYDROXYCAMPTOTHÉCINE
Abstract: front page image
(EN)A method of treating a resistant or refractory cancer in a mammal includes administering an effective amount of a compound of to the mammal. In preferred aspects, the cancer is resistant or refractory to CPT-1 1 or CPT therapy.
(FR)L'invention concerne un procédé de traitement d'un cancer résistant ou réfractaire chez un mammifère comprenant l'administration d'une quantité efficace d'un composé au mammifère. Dans des aspects préférés, le cancer est résistant ou réfractaire à une thérapie CPT-1 1 ou CPT.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)