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1. (WO2008098025) ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/098025    International Application No.:    PCT/US2008/053117
Publication Date: 14.08.2008 International Filing Date: 06.02.2008
IPC:
A01N 41/06 (2006.01), A61K 31/18 (2006.01)
Applicants: BOEHRINGER INGELHEIM INTERNATIONAL GMBH [DE/DE]; Binger Strasse 173, 55216 Ingelheim (DE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG [DE/DE]; Binger Strasse 173, 55216 Ingelheim (DE) (DE only).
THOMSON, David [GB/US]; (US) (For US Only).
RIETHER, Doris [AT/US]; (US) (For US Only).
ZINDELL, Renee, M. [US/US]; (US) (For US Only).
HICKEY, Eugene, Richard [US/US]; (US) (For US Only).
ERMANN, Monika [AT/GB]; (GB) (For US Only).
JENKINS, James, Edward [GB/GB]; (GB) (For US Only).
MUSHI, Innocent [TZ/GB]; (GB) (For US Only).
TAYLOR, Malcolm [GB/GB]; (GB) (For US Only).
AMOUZEGH, Patricia [FR/GB]; (GB) (For US Only).
WALKER, Edward [GB/GB]; (GB) (For US Only)
Inventors: THOMSON, David; (US).
RIETHER, Doris; (US).
ZINDELL, Renee, M.; (US).
HICKEY, Eugene, Richard; (US).
ERMANN, Monika; (GB).
JENKINS, James, Edward; (GB).
MUSHI, Innocent; (GB).
TAYLOR, Malcolm; (GB).
AMOUZEGH, Patricia; (GB).
WALKER, Edward; (GB)
Agent: MORRIS, Michael, P.; Boehringer Ingelheim Pharmaceuticals, Inc., 900 Ridgebury Road, P.O. Box 368, Ridgefield, CT 06877 (US)
Priority Data:
60/888,830 08.02.2007 US
Title (EN) ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR
(FR) COMPOSÉS ARYLSULFONAMIDE QUI MODULENT LE RÉCEPTEUR CB2
Abstract: front page image
(EN)Compounds are provided which bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, the compounds having the general formula (I) and the formula (IA) wherein, R1, R2, R3, R4, R5, R6, R7, R8 and X have the meanings given in the specification, and the preparation and use thereof. The compounds are valuable CB2 receptor modulators.
(FR)L'invention concerne des composés qui se lient à et sont des agonistes, des antagonistes ou des agonistes inverses du récepteur CB2, les composés ayant la formule générale (I) et la formule (IA) dans laquelle, R1, R2, R3, R4, R5, R6, R7, R8 et X ont les significations données dans le mémoire, et leur préparation et leur utilisation. Les composés sont des modulateurs de récepteur CB2 précieux.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)