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1. (WO2008097747) OPTICAL DETERMINATION OF PH AND GLUCOSE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/097747    International Application No.:    PCT/US2008/052204
Publication Date: 14.08.2008 International Filing Date: 28.01.2008
IPC:
G01N 33/66 (2006.01), G01N 33/84 (2006.01)
Applicants: GLUMETRICS, INC. [US/US]; 15375 Barranca Parkway, Suite I-108, Irvine, CA 92618 (US) (For All Designated States Except US).
MARKLE, David, R. [US/US]; (US) (For US Only).
SURI, Jeff, T. [US/US]; (US) (For US Only).
WESSLING, Ritchie, A. [US/US]; (US) (For US Only).
ROMEY, Matthew, A. [US/US]; (US) (For US Only)
Inventors: MARKLE, David, R.; (US).
SURI, Jeff, T.; (US).
WESSLING, Ritchie, A.; (US).
ROMEY, Matthew, A.; (US)
Agent: ALTMAN, Daniel, E.; Knobbe, Martens, Olson & Bear, LLP, 2040 Main Street, 14th Floor, Irvine, CA 92614 (US)
Priority Data:
11/671,880 06.02.2007 US
Title (EN) OPTICAL DETERMINATION OF PH AND GLUCOSE
(FR) DÉTERMINATION OPTIQUE DE PH ET DE GLUCOSE
Abstract: front page image
(EN)Embodiments of the present invention are directed to an optical sensor capable of measuring two analytes simultaneously with a single indicator system. In preferred embodiments, the sensor comprises a fluorescent dye having acid and base forms that facilitate ratiometric pH sensing, wherein the dye is further associated with a glucose binding moiety and configured to generate a signal that varies in intensity with the concentration of glucose.
(FR)L'invention concerne un capteur optique qui est capable de mesurer simultanément deux analytes avec un système d'indicateur unique. Selon des modes préférés de réalisation, le capteur comprend un colorant fluorescent ayant des formes acides et basiques qui facilitent une détection de pH ratiométrique, de sorte que le colorant est en outre associé à un fragment de liaison au glucose et configuré pour générer un signal qui varie en intensité avec la concentration de glucose.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)