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Pub. No.:    WO/2008/096831    International Application No.:    PCT/JP2008/052070
Publication Date: 14.08.2008 International Filing Date: 07.02.2008
Chapter 2 Demand Filed:    03.12.2008    
A61K 39/39 (2006.01), A61K 39/00 (2006.01), A61K 39/102 (2006.01), A61K 39/12 (2006.01), A61K 39/29 (2006.01), A61P 31/12 (2006.01), A61P 35/00 (2006.01), C07K 14/235 (2006.01), C07K 14/82 (2006.01)
Applicants: THE RESEARCH FOUNDATION FOR MICROBIAL DISEASES OF OSAKA UNIVERSITY [JP/JP]; c/o OSAKA UNIVERSITY, 3-1, Yamadaoka, Suita-shi, Osaka 5650871 (JP) (For All Designated States Except US).
National University Corporation Kochi University [JP/JP]; 5-1, Akebono-cho 2-chome, Kochi-shi, Kochi 7808520 (JP) (For All Designated States Except US).
UDAKA, Keiko [JP/JP]; (JP) (For US Only).
ISHIBASHI, Masahide [JP/JP]; (JP) (For US Only)
Inventors: UDAKA, Keiko; (JP).
ISHIBASHI, Masahide; (JP)
Agent: TAKASHIMA, Hajime; Meiji Yasuda Seimei Osaka Midosuji Bldg., 1-1, Fushimimachi 4-chome, Chuo-ku, Osaka-shi, Osaka 5410044 (JP)
Priority Data:
2007-028081 07.02.2007 JP
(JA) 癌の治療剤
Abstract: front page image
(EN)Disclosed are a cancer antigen peptide vaccine and an adjuvant for a virus antigen peptide, each of which comprises a pertussis vaccine as the main ingredient. Also disclosed is an agent for the treatment of cancer or a viral infection or for the prevention of the metastasis or recurrence of cancer or a virus-induced tumor, which comprises a cancer antigen peptide or a virus antigen peptide and a pertussis vaccine. A whole cell pertussis vaccine can be particularly preferably used as the pertussis vaccine. The agent is safe for multiple times of administration.
(FR)La présente invention concerne un vaccin peptidique d'antigène du cancer et un adjuvant du peptide de l'antigène du virus, chacun comprenant un vaccin contre la coqueluche en tant que principal ingrédient. L'invention porte aussi sur un agent thérapeutique contre le cancer ou une infection virale, ou destiné à prévenir la métastase ou la récurrence du cancer ou d'une tumeur induite par un virus, qui comprend un peptide d'antigène du cancer ou un peptide d'antigène du virus et un vaccin contre la coqueluche. Il peut être préférable d'utiliser notamment un vaccin contre la coqueluche à cellules entières. L'agent peut être administré en toute sécurité à plusieurs reprises.
(JA) 本発明は、百日咳ワクチンを主成分とする、癌抗原ペプチドワクチンおよびウイルス抗原ペプチド用アジュバントを提供する。本発明はまた、癌抗原ペプチドもしくはウイルス抗原ペプチドおよび百日咳ワクチンを含む、癌もしくはウイルス感染症の治療、並びに癌の転移や再発もしくはウイルス誘発性腫瘍の予防剤を提供する。百日咳ワクチンとしては、特に全菌体百日咳ワクチンが好適に用いられ得る。本発明の剤は、安全に複数回投与が可能である。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)