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1. (WO2008096730) ANTI-INFLAMMATORY AGENT AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/096730    International Application No.:    PCT/JP2008/051818
Publication Date: 14.08.2008 International Filing Date: 05.02.2008
IPC:
A61K 31/19 (2006.01), A23L 1/30 (2006.01), A61K 31/573 (2006.01), A61P 1/00 (2006.01), A61P 11/00 (2006.01), A61P 11/06 (2006.01), A61P 11/08 (2006.01), A61P 17/00 (2006.01), A61P 29/00 (2006.01)
Applicants: National University Corporation Nagoya University [JP/JP]; 1, Furo-cho, Chikusa-ku, Nagoya-shi, Aichi 4648601 (JP) (For All Designated States Except US).
ISHIGURO, Kazuhiro [JP/JP]; (JP) (For US Only).
GOTOH, Hidemi [JP/JP]; (JP) (For US Only).
ANDOH, Takahumi [JP/JP]; (JP) (For US Only)
Inventors: ISHIGURO, Kazuhiro; (JP).
GOTOH, Hidemi; (JP).
ANDOH, Takahumi; (JP)
Agent: HAGINO, Mikiharu; Annextechno2 1-21 technoplaza, Kakamigahara-shi Gifu 5090109 (JP)
Priority Data:
2007-030067 09.02.2007 JP
Title (EN) ANTI-INFLAMMATORY AGENT AND USE THEREOF
(FR) AGENT ANTI-INFLAMMATOIRE ET SON UTILISATION
(JA) 抗炎症剤及びその用途
Abstract: front page image
(EN)Disclosed are: a novel anti-inflammatory agent; and use of the anti-inflammatory agent. Specifically disclose is an anti-inflammatory agent comprising acetic acid or a salt thereof as the main component. The anti-inflammatory agent can exhibit its anti-inflammatory effect through the specific inhibition of the activation of a transcription factor NFAT. When the anti-inflammatory agent is used in combination with a steroidal anti-inflammatory agent, a higher therapeutic effect can be produced.
(FR)L'invention concerne un nouvel agent anti-inflammatoire et l'utilisation de l'agent anti-inflammatoire. De façon spécifique, l'invention concerne un agent anti-inflammatoire comprenant de l'acide acétique ou un sel de celui-ci comme composant principal. L'agent anti-inflammatoire peut présenter son effet anti-inflammatoire grâce à l'inhibition spécifique de l'activation d'un facteur de transcription NFAT. Lorsque l'agent anti-inflammatoire est utilisé en combinaison avec un agent anti-inflammatoire stéroïdien, un effet thérapeutique supérieur peut être obtenu.
(JA) 新規抗炎症剤及びその用途を提供することを課題とする。酢酸又は酢酸の塩を主成分として含有する抗炎症剤が提供される。本発明の抗炎症剤は転写因子NFATの活性化を特異的に抑制することにより抗炎症作用を発揮する。ステロイド系抗炎症剤を組み合わせることによって一層の治療的効果が得られる。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)