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Pub. No.:    WO/2008/096231    International Application No.:    PCT/IB2008/000250
Publication Date: 14.08.2008 International Filing Date: 29.01.2008
C07C 381/00 (2006.01), A01N 41/12 (2006.01)
Applicants: PFIZER LIMITED [GB/GB]; Ramsgate Road, Sandwich, Kent CT13 9NJ (GB) (For All Designated States Except US).
COMLAY, Stuart, Nicholas [GB/GB]; (GB) (For US Only).
HANNAM, Joanne, Clare [GB/GB]; (GB) (For US Only).
HOWSON, William [GB/GB]; (GB) (For US Only).
LAURET, Christelle [FR/GB]; (GB) (For US Only).
SABNIS, Yogesh, Anil [IN/GB]; (GB) (For US Only)
Inventors: COMLAY, Stuart, Nicholas; (GB).
HANNAM, Joanne, Clare; (GB).
HOWSON, William; (GB).
LAURET, Christelle; (GB).
SABNIS, Yogesh, Anil; (GB)
Agent: DROUIN, Stéphane; Pfizer Global Research and Devolpment, Ramsgate Road, Sandwich, Kent, CT13 9NJ (GB)
Priority Data:
60/889,041 09.02.2007 US
60/946,820 28.06.2007 US
Abstract: front page image
(EN)The present invention relates to compounds of the formula (I) or a tautomer or prodrug thereof, or a pharmaceutically acceptable salt of said compound, tautomer or prodrug, wherein: R1, R2, R3, R4 and R5 are each independently selected from H, halo, CN, CF3 and CONH2; compositions containing such compounds and the uses of such compounds as antiparasitic agents.
(FR)La présente invention concerne des composés de formule (I) (I) ou l'un de leurs tautomères ou précurseurs ou un sel acceptable sur le plan pharmaceutique dudit composé, tautomère ou précurseur, où : R1, R2, R3, R4 et R5 sont chacun choisis indépendamment parmi H, halogéno, CN, CF3 et CONH2; des compositions contenant de tels composés et les utilisations de tels composés en tant qu'agents antiparasitaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)