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1. WO2008096149 - NAPADISYLATE SALT OF A MUSCARINIC M3 ANTAGONIST

Publication Number WO/2008/096149
Publication Date 14.08.2008
International Application No. PCT/GB2008/000434
International Filing Date 06.02.2008
IPC
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
D
HETEROCYCLIC COMPOUNDS
263
Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
02
not condensed with other rings
08
having one double bond between ring members or between a ring member and a non-ring member
10
with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
12
with radicals containing only hydrogen and carbon atoms
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
421
1,3-Oxazoles, e.g. pemoline, trimethadione
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
C07D 263/12 (2006.01)
A61K 31/421 (2006.01)
A61P 11/06 (2006.01)
CPC
C07D 263/32
Applicants
  • ARGENTA DISCOVERY LTD [GB/GB]; 8/9 Spire Green Centre Flex Meadow Harlow Essex CM19 5TR, GB (AllExceptUS)
  • ASTRAZENECA AB [SE/SE]; S-0151 85 Soderjalje, SE (AllExceptUS)
  • AVITABILE, Barbara, Giuseppina [IT/GB]; GB (UsOnly)
  • O'SULLIVAN, David [GB/GB]; GB (UsOnly)
  • BULL, Richard, James [GB/GB]; GB (UsOnly)
Inventors
  • AVITABILE, Barbara, Giuseppina; GB
  • O'SULLIVAN, David; GB
  • BULL, Richard, James; GB
Agents
  • CELEBIOGLU, Sonya ; AstraZeneca AB AstraZeneca Intellectual Property SE-151 85 Sodertalje, SE
Priority Data
0702385.607.02.2007GB
0702416.907.02.2007GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NAPADISYLATE SALT OF A MUSCARINIC M3 ANTAGONIST
(FR) SEL INÉDIT
Abstract
(EN)
The invention provides [2-(4-chloro-benzyloxy)-ethyl]-[2-((R)-cyclohexyl-hydroxy- phenyl-methyl)-oxazol-5-ylmethyl]-dimethyl-ammonium napadisylate, pharmaceutical compositions containing it, and its use in therapy.
(FR)
La présente invention concerne le diméthylammonium napadisylate de [2-(4-chloro-benzyloxy)-éthyl]-[2-((R)-cyclohexyl-hydroxy-phényl-méthyl)-oxazol-5-ylméthyl], des compositions pharmaceutiques en contenant et son utilisation à des fins thérapeutiques.
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