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1. (WO2008096136) COMBINATIONS WITH A MUSCARINIC RECEPTOR ANTAGONIST
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2008/096136 International Application No.: PCT/GB2008/000415
Publication Date: 14.08.2008 International Filing Date: 06.02.2008
IPC:
A61K 31/421 (2006.01) ,A61K 31/4468 (2006.01) ,A61P 11/06 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
41
having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42
Oxazoles
421
1,3-Oxazoles, e.g. pemoline, trimethadione
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
33
Heterocyclic compounds
395
having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
435
having six-membered rings with one nitrogen as the only ring hetero atom
44
Non-condensed pyridines; Hydrogenated derivatives thereof
445
Non-condensed piperidines, e.g. piperocaine
4468
having a nitrogen atom directly attached in position 4, e.g. clebopride, fentanyl
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11
Drugs for disorders of the respiratory system
06
Antiasthmatics
Applicants:
DIXON, John [GB/GB]; GB (UsOnly)
ERIKSSON, Tomas [SE/SE]; SE (UsOnly)
HANSSON, John [SE/SE]; SE (UsOnly)
MENSONIDES-HARSEMA, Marguerite [NL/SE]; SE (UsOnly)
MO, John [SE/SE]; SE (UsOnly)
FINCH, Harry [GB/GB]; GB (UsOnly)
ARGENTA DISCOVERY LTD [GB/GB]; 8/9 Spire Green Centre Flex Meadow Harlow Essex CM19 5TR, GB (AllExceptUS)
ASTRAZENECA AB [SE/SE]; S-151 85 Sodertalje, SE (AllExceptUS)
Inventors:
DIXON, John; GB
ERIKSSON, Tomas; SE
HANSSON, John; SE
MENSONIDES-HARSEMA, Marguerite; SE
MO, John; SE
FINCH, Harry; GB
Agent:
MERCER, Christopher, Paul ; Carpmaels & Ransford 43-45 Bloomsbury Square London WC1A 2RA, GB
Priority Data:
0702416.907.02.2007GB
60/891,24523.02.2007US
Title (EN) COMBINATIONS WITH A MUSCARINIC RECEPTOR ANTAGONIST
(FR) COMBINAISON INÉDITE
Abstract:
(EN) The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is a selected muscarinic receptor antagonist, and a second active ingredient which is selected from a phosphodiesterase inhibitor, a modulator of chemokine receptor function, an inhibitor of kinase function, a protease inhibitor, a steroidal glucocorticoid receptor agonist, a non-steroidal glucocorticoid receptor agonist and a purinoceptor antagonist, of use in the treatment of respiratory diseases such as chronic obstructive pulmonary disease and asthma.
(FR) La présente invention a trait à un produit, une trousse ou une composition pharmaceutique comprenant un premier principe actif, qui est un antagoniste d'un récepteur muscarinique sélectionné, et un second principe actif, qui est choisi parmi un inhibiteur de la phosphodiestérase, un modulateur de l'action du récepteur des chimiokines, un inhibiteur de l'activité kinase, un inhibiteur des protéases, un agoniste stéroïdien du récepteur des glucocorticoïdes, un agoniste non stéroïdien du récepteur des glucocorticoïdes et un antagoniste du purinocepteur, utilisable dans le cadre du traitement de maladies respiratoires comme la bronchopneumopathie chronique obstructive et l'asthme.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)