WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |

Search International and National Patent Collections
World Intellectual Property Organization
Machine translation
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/096121    International Application No.:    PCT/GB2008/000396
Publication Date: 14.08.2008 International Filing Date: 06.02.2008
A61K 31/428 (2006.01)
Applicants: ASTRAZENECA AB [SE/SE]; S-151 85 Södertälje (SE) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
ASTRAZENECA UK LIMITED [GB/GB]; 15 Stanhope Gate, London Greater London W1K 1LN (GB) (MG only).
CADOGAN, Elaine, Bridget [IE/GB]; (GB) (For US Only).
CONNOLLY, Stephen [GB/GB]; (GB) (For US Only).
NICHOLLS, David, John [GB/GB]; (GB) (For US Only).
WILEY, Katherine, Elisabeth [GB/GB]; (GB) (For US Only).
YOUNG, Alan [GB/GB]; (GB) (For US Only)
Inventors: CADOGAN, Elaine, Bridget; (GB).
CONNOLLY, Stephen; (GB).
NICHOLLS, David, John; (GB).
WILEY, Katherine, Elisabeth; (GB).
YOUNG, Alan; (GB)
Agent: ASTRAZENECA INTELLECTUAL PROPERTY; AstraZeneca AB, S-151 85 Södertälje (SE)
Priority Data:
0702457.3 08.02.2007 GB
Abstract: front page image
(EN)The invention provides a pharmaceutical product, kit or composition comprising a first active ingredient which is N-[2-(Diethylamino)ethyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)ethyl]amino}ethyl)-3-[2-(3-chlorophenyl)ethoxy]pro panamide or a salt thereof, and a second active ingredient selected from: a non-steroidal Glucocorticoid Receptor (GR Receptor) Agonist; an antioxidant; a CCR1 antagonist; a chemokine antagonist (not CCR1); a corticosteroid; a CRTh2 antagonist; a DP1 antagonist; an Histone Deacetylase Inducer; an IKK2 inhibitor; a COX inhibitor; a lipoxygenase inhibitor; a leukotriene receptor antagonist; an MPO inhibitor; a muscarinic antagonist; a p38 inhibitor; a PDE inhibitor; a PPAR&Ugr; agonist; a protease inhibitor; a Statin; a thromboxane antagonist; a vasodilator; or, an ENAC blocker (Epithelial Sodium-channel blocker); and its use in the treatment of respiratory disease.
(FR)L'invention concerne un produit pharmaceutique, une trousse ou une composition renfermant un premier ingrédient actif qui est un N-[2-(Diéthylamino)éthyl]-N-(2-{[2-(4-hydroxy-2-oxo-2,3-dihydro-1,3-benzothiazol-7-yl)éthyl]amino}éthyl)-3-[2-(3-chlorophényl)ethoxy]pro panamide ou un sel de ce dernier, et un second ingrédient actif choisi entre: un agoniste non stéroïdien du récepteur des glucocorticoïdes (récepteur GR); un antioxydant; un antagoniste CCR1; un antagoniste de la chimiokine (pas CCR1); un corticostéroïde; un antagoniste CRTh2; un antagoniste DP1; un inducteur de l'histone désacétylase; un inhibiteur IKK2; un inhibiteur COX; un inhibiteur de la lipoxygénase; un antagoniste du récepteur de leucotriène; un inhibiteur MPO; un antagoniste muscarinique; un inhibiteur de p38; un inhibiteur PDE; un agoniste PPAR&ggr;; un inhibiteur de protéase; une statine; un antagoniste de la thromboxane; un vasodilatateur; ou un bloqueur ENAC ('Epithelial Sodium-channel blocker' ou bloqueur du canal sodium épithélial); et l'utilisation dudit produit pharmaceutique dans le traitement de la maladie respiratoire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)