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1. (WO2008095809) NITRIC OXIDE RELEASING STEROIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/095809    International Application No.:    PCT/EP2008/050948
Publication Date: 14.08.2008 International Filing Date: 28.01.2008
IPC:
C07J 41/00 (2006.01), A61K 31/573 (2006.01), A61P 5/44 (2006.01)
Applicants: NICOX S.A. [FR/FR]; Taissounières HB4 -, 1681 route des Dolines - BP313, F-06560 Sophia Antipolis -valbonne (FR) (For All Designated States Except US).
BENEDINI, Francesca [IT/IT]; (IT) (For US Only).
BIONDI, Stefano [IT/IT]; (IT) (For US Only).
ONGINI, Ennio [IT/IT]; (IT) (For US Only)
Inventors: BENEDINI, Francesca; (IT).
BIONDI, Stefano; (IT).
ONGINI, Ennio; (IT)
Agent: BARCHIELLI, Giovanna; Nicox Research Institute Srl, Via L. Ariosto 21, I-20091 Bresso (Milano) (IT)
Priority Data:
60/899,376 05.02.2007 US
60/929,456 28.06.2007 US
Title (EN) NITRIC OXIDE RELEASING STEROIDS
(FR) STÉROÏDES LIBÉRANT DE L'OXYDE NITRIQUE
Abstract: front page image
(EN)The invention relates to nitrooxyderivative of corticosteroids of general formula (I) and pharmaceutically acceptable salts or stereoisomers thereof wherein R is the corticosteroid residue of formula (II): The compounds are useful in the treatment of respiratory diseases, inflammatory diseases, dermatological diseases and oculardiseases.
(FR)La présente invention concerne un dérivé nitro-oxy de corticostéroïdes de formule générale (I) et ses sels ou stéréo-isomères acceptables sur le plan pharmaceutique où R représente le résidu de corticostéroïde de formule (II) : Les composés sont utiles dans le traitement de maladies respiratoires, de maladies inflammatoires, de maladies dermatologiques et de maladies oculaires.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)