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1. (WO2008095366) PORPHYRIN DERIVATIVES, PREPARATION METHODS AND THE USES AS SMALL MOLECULAR ANTIOXIDANT THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/095366    International Application No.:    PCT/CN2007/002970
Publication Date: 14.08.2008 International Filing Date: 17.10.2007
IPC:
C07D 487/22 (2006.01), A61K 31/409 (2006.01), A61K 31/555 (2006.01), A61P 39/06 (2006.01), A61P 35/00 (2006.01), A61P 3/10 (2006.01), A61P 7/02 (2006.01), A61P 19/02 (2006.01), A61P 25/16 (2006.01), A61P 31/18 (2006.01), A61P 17/18 (2006.01)
Applicants: JINAN SAIWEN PHARMTECHNOLOGY INC. [CN/CN]; C503 No 69 Huayang Road Jinan Shandong 250100 (CN) (For All Designated States Except US).
GONG, Xianchang [CN/CN]; (CN) (For US Only).
HU, Taiyou [CN/CN]; (CN) (For US Only).
DONG, Changzhi [CN/CN]; (CN) (For US Only).
GUO, Tianshun [CN/CN]; (CN) (For US Only).
SONG, Caiyan [CN/CN]; (CN) (For US Only).
DENG, Zhiping [CN/CN]; (CN) (For US Only)
Inventors: GONG, Xianchang; (CN).
HU, Taiyou; (CN).
DONG, Changzhi; (CN).
GUO, Tianshun; (CN).
SONG, Caiyan; (CN).
DENG, Zhiping; (CN)
Agent: CN-KNOWHOW INTELLECTUAL PROPERTY AGENT LIMITED; Suite 707 Fortune International Center No. 17 Daliushu Road Beijing 100081 (CN)
Priority Data:
200710006441.2 02.02.2007 CN
Title (EN) PORPHYRIN DERIVATIVES, PREPARATION METHODS AND THE USES AS SMALL MOLECULAR ANTIOXIDANT THEREOF
(FR) DÉRIVÉS DE PORPHYRINE, LEURS MÉTHODES DE PRÉPARATION ET LEURS UTILISATIONS COMME MOLÉCULE ANTIOXYDANTE DE PETITE TAILLE
(ZH) 一种卟啉衍生物、其制备方法及其作为小分子抗氧化剂的应用
Abstract: front page image
(EN)A porphyrin derivative and its pharmaceutical acceptable salt and its preparation method. The said porphyrin derivative is M-5,10,15,20-tetra[3-ethylene polyol monomethyl ether-substituted -phenyl]porphyrin, in which M is one of Fe, Mn, Co, Ni, Cu, Zn, Sn, Cr, V and Pt metal ions. The said porphyrin derivative can be used as small molecular antioxidant for regulating the concentration of peroxide between cells of human body or in cell, protecting the body to avoid the damage from peroxy radical or from other peroxide derived from peroxy radical, preventing or treating the diseases caused by the peroxide.
(FR)L'invention concerne un dérivé de porphyrine, son sel de qualité pharmaceutique et sa méthode de préparation. Ce dérivé de porphyrine est une M-5, 10, 15, 20-tétra[3-éthylène polyol monométhyle éther-substituée-phényle]porphyrine, dans lequel M désigne un des ions métalliques suivants: Fe, Mn, Co, Ni, Cu, Zn, Sn, Cr, V et Pt. Ce dérivé de porphyrine peut être utilisé comme molécule antioxydante de petite taille pour réguler la concentration de peroxyde entre les cellules du corps humainou dans une cellule, afin de protéger le corps contre les dommages provoqués par les radicaux peroxy ou d'autres peroxydes dérivés du radical peroxy, et également afin de prévenir ou de traiter les maladies dues au peroxyde.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Chinese (ZH)
Filing Language: Chinese (ZH)