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1. (WO2008094690) METHODS FOR PREPARING ESZOPICLONE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/094690    International Application No.:    PCT/US2008/001372
Publication Date: 07.08.2008 International Filing Date: 31.01.2008
IPC:
C07D 401/14 (2006.01)
Applicants: TEVA PHARMACEUTICAL INDUSTRIES LTD. [IL/IL]; 5 Basel Street, P.O. Box 3190, 49131 Petah Tiqva (IL) (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BE, BF, BG, BH, BJ, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CM, CN, CO, CR, CU, CY, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IS, IT, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SI, SK, SL, SM, SN, SV, SY, SZ, TD, TG, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW only).
TEVA PHARMACEUTICALS USA, INC. [US/US]; 1090 Horsham Road, P.o. Box 1090, North Wales, PA 19454-1090 (US) (BB only).
FINKELSTEIN, Nina [IL/IL]; (IL) (For US Only).
MENDELOVICI, Marioara [IL/IL]; (IL) (For US Only).
RAMATY, Revital [IL/IL]; (IL) (For US Only).
MAINFELD, Alex [IL/IL]; (IL) (For US Only)
Inventors: FINKELSTEIN, Nina; (IL).
MENDELOVICI, Marioara; (IL).
RAMATY, Revital; (IL).
MAINFELD, Alex; (IL)
Agent: BIRDE, Patrick, J.; Kenyon & Kenyon LLP, One Broadway, New York, NY 10004-1050 (US)
Priority Data:
60/898,405 31.01.2007 US
11/738,115 20.04.2007 US
60/929,682 09.07.2007 US
Title (EN) METHODS FOR PREPARING ESZOPICLONE
(FR) PROCÉDÉS DE PRÉPARATION D'ESZOPICLONE
Abstract: front page image
(EN)Methods for the preparation of crystalline eszopiclone free base in water, in the absence of organic solvents, are provided. The methods are more environmentally acceptable than prior art methods, and produce eszopiclone free base essentially free of residual organic solvent.
(FR)L'invention concerne des procédés pour la préparation de base libre d'eszopiclone cristalline dans l'eau, en l'absence de solvants organiques. Les procédés sont plus acceptables d'un point de vue environnemental que les procédés de l'art antérieur, et produisent une base libre d'eszopiclone essentiellement dépourvue de solvant organique résiduel.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)