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1. (WO2008094689) POTENTIATION OF STEM CELL HOMING AND TREATMENT OF ORGAN DYSFUNCTION OR ORGAN FAILURE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/094689    International Application No.:    PCT/US2008/001371
Publication Date: 07.08.2008 International Filing Date: 01.02.2008
IPC:
A61K 31/44 (2006.01)
Applicants: NEPHROGEN, LLC [US/US]; 615 Arapeen Drive, Suite 300, Salt Lake City, UT 84108 (US) (For All Designated States Except US).
WESTENFELDER, Christof [US/US]; (US) (For US Only)
Inventors: WESTENFELDER, Christof; (US)
Agent: MORRISS O'BRYANT COMPAGNI, P.C.; 734 East 200 South, Salt Lake City, UT 84102 (US)
Priority Data:
60/898,803 01.02.2007 US
Title (EN) POTENTIATION OF STEM CELL HOMING AND TREATMENT OF ORGAN DYSFUNCTION OR ORGAN FAILURE
(FR) POTENTIALISATION DE L'IMPLANTATION DE CELLULES SOUCHES ET TRAITEMENT D'UN DYSFONCTIONNEMENT D'ORGANE OU D'UNE INSUFFISANCE D'ORGANE
Abstract: front page image
(EN)The invention provides methods and compositions for the treatment of multi-organ failure or kidney dysfunction, such as acute renal failure, by mesenchymal stem cells and a CD26 inhibitor, where inhibition of CD26 increases homing of the mesenchymal stem cells to a target tissue.
(FR)L'invention concerne des procédés et des compositions permettant le traitement d'une insuffisance multi-viscérale ou d'un dysfonctionnement du foie, tel qu'une insuffisance rénale aiguë, par des cellules souches mésenchymateuses et un inhibiteur du CD26, où l'inhibition du CD26 accroît l'implantation des cellules souches mésenchymateuses sur un tissu cible.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)