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1. (WO2008094602) 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/094602    International Application No.:    PCT/US2008/001230
Publication Date: 07.08.2008 International Filing Date: 30.01.2008
IPC:
C07D 487/04 (2006.01), A61K 31/505 (2006.01), A61P 35/00 (2006.01)
Applicants: BIOGEN IDEC MA INC. [US/US]; 14 Cambridge Center, Cambridge, MA 02142 (US) (For All Designated States Except US).
KASIBHATLA, Srinivas, Rao [US/US]; (US) (For US Only).
HONG, Kevin [US/US]; (US) (For US Only).
ZHANG, Lin [US/US]; (US) (For US Only).
BOEHM, Marcus, F. [US/US]; (US) (For US Only).
FAN, Junhua [CN/US]; (US) (For US Only).
LE BRAZIDEC, Jean-Yves [FR/US]; (US) (For US Only)
Inventors: KASIBHATLA, Srinivas, Rao; (US).
HONG, Kevin; (US).
ZHANG, Lin; (US).
BOEHM, Marcus, F.; (US).
FAN, Junhua; (US).
LE BRAZIDEC, Jean-Yves; (US)
Agent: O'BRIEN, Jonathan, P.; Miller, Canfield, Paddock And Stone, P.L.C., 444 West Michigan Avenue, Kalamazoo, MI 49007 (US)
Priority Data:
60/898,300 30.01.2007 US
60/898,382 30.01.2007 US
Title (EN) 1-H-PYRAZOLO (3,4B) PYRIMIDINE DERIVATIVES AND THEIR USE AS MODULATORS OF MITOTIC KINASES
(FR) MODULATEURS DE KINASES MITOTIQUES
Abstract: front page image
(EN)The invention relates to compounds of Formula (I), a polymorph, an enantiomer, a stereoisomer, a solvate, an N-oxide derivative, or a pharmaceutically acceptable salt thereof: Formula (I), which have inhibitory effect on one or more protein kinases that are involved in cell mitosis.
(FR)L'invention concerne des composés représentés par la formule (I), un promédicament, un polymorphe, un tautomère, un énantiomère, un stéréoisomères, un solvate, un N-oxyde ou un sel pharmaceutiquement acceptable de ces composés : formule (I) qui possèdent un effet inhibiteur sur une ou plusieurs protéines kinases impliquées dans la mitose cellulaire.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)