Search International and National Patent Collections
Some content of this application is unavailable at the moment.
If this situation persists, please contact us atFeedback&Contact
1. (WO2008094183) USE OF CONDITIONAL PLASMODIUM STRAINS LACKING NUTRIENT TRANSPORTERS IN MALARIA VACCINATION
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2008/094183 International Application No.: PCT/US2007/015962
Publication Date: 07.08.2008 International Filing Date: 11.07.2007
IPC:
A61K 39/015 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
002
Protozoa antigens
015
Hemosporidia antigens, e.g. Plasmodium antigens
Applicants:
UNIVERSITY OF CONNECTICUT [US/US]; 263 Farmington Avenue Farmington, CT 06030-6207, US (AllExceptUS)
MAMOUN, Choukri, Ben [US/US]; US (UsOnly)
Inventors:
MAMOUN, Choukri, Ben; US
Agent:
PRATT, John, S. ; Kilpatrick Stockton Llp 1100 Peachtree Street Suite 2800 Atlanta, GA 30309, US
Priority Data:
60/830,37111.07.2006US
Title (EN) USE OF CONDITIONAL PLASMODIUM STRAINS LACKING NUTRIENT TRANSPORTERS IN MALARIA VACCINATION
(FR) UTILISATION DE SOUCHES DE PLASMODIUM CONDITIONNELLES EXEMPTES DE TRANSPORTEURS DE NUTRIMENTS DANS LA VACCINATION ANTI-PALUDIQUE
Abstract:
(EN) The present invention relates to a malaria vaccine for administration to a host comprising an attenuated malarial parasite with a gene which has been rendered non¬ functional, wherein the gene, when present in naturally occurring form, encodes a protein necessary for continued in vivo survival and proliferation of the parasite and for infection of host red blood cells. The invention further relates to a malaria vaccine in which a gene that encodes a nutrient transporter protein has been rendered non-functional.
(FR) La présente invention concerne un vaccin anti-paludique destiné à être administré à un hôte comprenant un parasite paludéen atténué avec un gène qui a été rendu non fonctionnel, ledit gène, lorsqu'il est présent sous forme naturelle, codant pour une protéine nécessaire à la survie et à la prolifération in vivo continue du parasite et à l'infection des globules rouges de l'hôte. L'invention comprend en outre un vaccin anti-paludique dans lequel un gène qui code pour une protéine transporteuse de nutriments a été rendu non fonctionnel.
front page image
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)