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Machine translation
1. (WO2008094183) USE OF CONDITIONAL PLASMODIUM STRAINS LACKING NUTRIENT TRANSPORTERS IN MALARIA VACCINATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/094183    International Application No.:    PCT/US2007/015962
Publication Date: 07.08.2008 International Filing Date: 11.07.2007
IPC:
A61K 39/015 (2006.01)
Applicants: UNIVERSITY OF CONNECTICUT [US/US]; 263 Farmington Avenue, Farmington, CT 06030-6207 (US) (For All Designated States Except US).
MAMOUN, Choukri, Ben [US/US]; (US) (For US Only)
Inventors: MAMOUN, Choukri, Ben; (US)
Agent: PRATT, John, S.; Kilpatrick Stockton Llp, 1100 Peachtree Street, Suite 2800, Atlanta, GA 30309 (US)
Priority Data:
60/830,371 11.07.2006 US
Title (EN) USE OF CONDITIONAL PLASMODIUM STRAINS LACKING NUTRIENT TRANSPORTERS IN MALARIA VACCINATION
(FR) UTILISATION DE SOUCHES DE PLASMODIUM CONDITIONNELLES EXEMPTES DE TRANSPORTEURS DE NUTRIMENTS DANS LA VACCINATION ANTI-PALUDIQUE
Abstract: front page image
(EN)The present invention relates to a malaria vaccine for administration to a host comprising an attenuated malarial parasite with a gene which has been rendered non¬ functional, wherein the gene, when present in naturally occurring form, encodes a protein necessary for continued in vivo survival and proliferation of the parasite and for infection of host red blood cells. The invention further relates to a malaria vaccine in which a gene that encodes a nutrient transporter protein has been rendered non-functional.
(FR)La présente invention concerne un vaccin anti-paludique destiné à être administré à un hôte comprenant un parasite paludéen atténué avec un gène qui a été rendu non fonctionnel, ledit gène, lorsqu'il est présent sous forme naturelle, codant pour une protéine nécessaire à la survie et à la prolifération in vivo continue du parasite et à l'infection des globules rouges de l'hôte. L'invention comprend en outre un vaccin anti-paludique dans lequel un gène qui code pour une protéine transporteuse de nutriments a été rendu non fonctionnel.
Designated States: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)