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1. (WO2008093958) METHOD OF PRODUCING EXTRACT OF HORSE CHESTNUT LEAF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/093958    International Application No.:    PCT/KR2008/000412
Publication Date: 07.08.2008 International Filing Date: 23.01.2008
IPC:
A61K 36/185 (2006.01), A61K 8/97 (2006.01)
Applicants: ANGIOLAB., INC. [KR/KR]; Bio-Diagnostic Fusion Center, Expo Park, 3-1, Doryong-dong, Yuseong-gu, Daejeon 305-340 (KR) (For All Designated States Except US).
KIM, Min-Young [KR/KR]; (KR).
HAHM, Jong-Cheon [KR/KR]; (KR) (For US Only).
PARK, Byung-Young [KR/KR]; (KR) (For US Only).
PARK, Eun-Kyu [KR/KR]; (KR) (For US Only).
LEE, Hee-Suk [KR/KR]; (KR) (For US Only)
Inventors: KIM, Min-Young; (KR).
HAHM, Jong-Cheon; (KR).
PARK, Byung-Young; (KR).
PARK, Eun-Kyu; (KR).
LEE, Hee-Suk; (KR)
Agent: AHN, So-Young; Dr. Ahn International Patent Law Office, 10th Fl. Shinseung Bldg., 1676-1, Seocho-dong, Seocho-gu, Seoul 137-881 (KR)
Priority Data:
10-2007-0009082 29.01.2007 KR
Title (EN) METHOD OF PRODUCING EXTRACT OF HORSE CHESTNUT LEAF
(FR) PROCÉDÉ DE PRODUCTION D'EXTRAIT DE FEUILLES DE MARRONNIER D'INDE
Abstract: front page image
(EN)The present invention provide a method of producing extract of Horse chestnut leaf comprising following steps: 1) drying and crushing horse chestnut leaves; 2) subjecting crushed horse chestnut leaves to extraction with a 25% aqueous alcohol with heating; 3) filtering the aqueous extract from step 2); and 4) concentrating the filtrate from step 3) to recover the extract, and a composition comprising the extract as an active ingredient for treating or preventing MMPs-dependent diseases including periodontal disease.
(FR)L'invention concerne un procédé de production d'extrait de feuilles de marronnier d'inde qui consiste: 1) à sécher et broyer les feuilles de marronnier d'inde; 2) à extraire les feuilles de marronnier d'inde ainsi broyées par traitement thermique avec 25% d'alcool aqueux; 3) à filtrer l'extrait aqueux obtenu en (2); et 4) à concentrer le filtrat obtenu en (3) pour récupérer l'extrait. Par ailleurs, l'invention concerne une composition renfermant cet extrait comme principe actif, qui est destinée à traiter ou prévenir des maladies liées aux métalloprotéinases de la matrice (MMP).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)