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1. (WO2008093940) QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/093940    International Application No.:    PCT/KR2008/000202
Publication Date: 07.08.2008 International Filing Date: 11.01.2008
IPC:
C07D 401/04 (2006.01)
Applicants: YUNGJIN PHARMACEUTICAL CO., LTD. [KR/KR]; 451-20 Cheonho-dong, Gangdong-gu, Seoul 134-864 (KR) (For All Designated States Except US).
HAN, Je Wook [KR/KR]; (KR) (For US Only).
KIM, Sung Gyu [KR/KR]; (KR) (For US Only).
SHIN, Min Ki [KR/KR]; (KR) (For US Only).
SOHN, Sang Kwon [KR/KR]; (KR) (For US Only).
JUNG, Yoon Sung [KR/KR]; (KR) (For US Only).
HA, Ni Na [KR/KR]; (KR) (For US Only).
KIM, Jong Hwan [KR/KR]; (KR) (For US Only)
Inventors: HAN, Je Wook; (KR).
KIM, Sung Gyu; (KR).
SHIN, Min Ki; (KR).
SOHN, Sang Kwon; (KR).
JUNG, Yoon Sung; (KR).
HA, Ni Na; (KR).
KIM, Jong Hwan; (KR)
Agent: AJU INTERNATIONAL LAW & PATENT GROUP; 12th Floor, Poonglim Building, 823-1, Yeoksam-dong, Gangnam-gu, Seoul 135-784 (KR)
Priority Data:
10-2007-0010137 31.01.2007 KR
Title (EN) QUINOLINE DERIVATIVES AS CASPASE-3 INHIBITOR, PREPARATION PROCESS FOR THE SAME AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME
(FR) DÉRIVÉS DE QUINOLÉINE EN TANT QU'INHIBITEURS DE LA CASPASE 3, PROCÉDÉ DE PRÉPARATION ET COMPOSITION PHARMACEUTIQUE LES CONTENANT
Abstract: front page image
(EN)Provided is a quinoline derivative represented by the following Formula (1) for use in treating a caspase- mediated disease by inhibition of caspase-3 activity. Further provided are a method for preparing the quinoline derivative or a pharmaceutically acceptable salt thereof and a pharmaceutical composition containing the same.
(FR)La présente invention concerne un dérivé de quinoléine représenté par la formule (1) à utiliser dans le traitement d'une maladie médiée par une caspase par l'inhibition de l'activité de la caspase 3. En outre, l'invention concerne un procédé de préparation du dérivé de quinoléine ou de l'un de ses sels acceptables sur le plan pharmaceutique et une composition pharmaceutique le contenant.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: Korean (KO)