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1. (WO2008092939) PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPARATION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/092939    International Application No.:    PCT/EP2008/051230
Publication Date: 07.08.2008 International Filing Date: 31.01.2008
IPC:
C07D 401/12 (2006.01)
Applicants: KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO [SI/SI]; Smarjeska cesta 6, 8501 Novo Mesto (SI) (For All Designated States Except US).
PLAPER, Igor [SI/SI]; (SI) (For US Only).
PECAVAR, Anica [SI/SI]; (SI) (For US Only).
KOTAR-JORDAN, Berta [SI/SI]; (SI) (For US Only).
ZAJC, Natalija [SI/SI]; (SI) (For US Only).
VRBINC, Miha [SI/SI]; (SI) (For US Only).
KOCEVAR, Anton [SI/SI]; (SI) (For US Only).
PELKO, Mitja [SI/SI]; (SI) (For US Only).
VEVERKA, Miroslav [SK/SK]; (SK) (For US Only).
VEVERKOVÁ, Eva [SK/SK]; (SK) (For US Only).
SMODIS, Janez [SI/SI]; (SI) (For US Only).
ZUPET, Rok [SI/SI]; (SI) (For US Only)
Inventors: PLAPER, Igor; (SI).
PECAVAR, Anica; (SI).
KOTAR-JORDAN, Berta; (SI).
ZAJC, Natalija; (SI).
VRBINC, Miha; (SI).
KOCEVAR, Anton; (SI).
PELKO, Mitja; (SI).
VEVERKA, Miroslav; (SK).
VEVERKOVÁ, Eva; (SK).
SMODIS, Janez; (SI).
ZUPET, Rok; (SI)
Agent: UEXKÜLL & STOLBERG; Beselerstr. 4, 22607 Hamburg (DE)
Priority Data:
P-200700024 31.01.2007 SI
P-200700078 28.03.2007 SI
07019823.9 10.10.2007 EP
Title (EN) PROCESS FOR THE PREPARATION OF OPTICALLY PURE OMEPRAZOLE VIA SALT FORMATION WITH A CHIRAL AMINE OR TREATMENT WITH AN ENTIOMER CONVERTING ENZYME AND CHROMATOGRAPHIC SEPARATION
(FR) PROCÉDÉ DE PRÉPARATION D'OMÉPRAZOLE OPTIQUEMENT PUR
Abstract: front page image
(EN)The present invention relates to a process for the preparation of substantially optically pure omeprazole, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to a process for preparing a pharmaceutical composition comprising the substantially optically pure omeprazole or the pharmaceutically acceptable salt or solvate thereof and to intermediates useful for the preparation of optically pure omeprazole.
(FR)La présente invention concerne un procédé de préparation d'oméprazole substantiellement optiquement pur, ou d'un sel ou d'un solvate pharmaceutiquement acceptable de celui-ci. L'invention concerne également un procédé de préparation d'une composition pharmaceutique comprenant l'oméprazole substantiellement optiquement pur ou un sel ou un solvate pharmaceutiquement acceptable de celui-ci et des intermédiaires utiles pour la préparation d'oméprazole optiquement pur.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)