WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2008092877) 8-OXA-1, 4-DIAZASPIRO [4,5] DEC-3-EN-1-YL AND 1,4, 8-TRIAZASPIRO [4,5] DEC- 3-EN-1-YL ACETAMIDES AS GLYTI TRANSPORTER INHIBITORS IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/092877    International Application No.:    PCT/EP2008/051083
Publication Date: 07.08.2008 International Filing Date: 30.01.2008
IPC:
C07D 471/10 (2006.01), C07D 491/10 (2006.01), A61K 31/438 (2006.01), A61K 31/4188 (2006.01), A61P 25/18 (2006.01), A61P 25/28 (2006.01)
Applicants: GLAXO GROUP LIMITED [GB/GB]; Glaxo Wellcome House, Berkeley Avenue, Greenford, Middlesex UB6 0NN (GB) (For All Designated States Except US).
UNIVERSITY OF NOTTINGHAM [GB/GB]; University Park, Nottingham NG7 2RD (GB) (For All Designated States Except US).
AHMAD, Nadia Mamoona [GB/GB]; (GB) (For US Only).
LAI, Justine, Yeun Quai [SG/GB]; (GB) (For US Only).
MARSHALL, Howard, Robert [GB/GB]; (GB) (For US Only).
NASH, David, John [GB/GB]; (GB) (For US Only).
PORTER, Roderick, Alan [GB/GB]; (GB) (For US Only)
Inventors: AHMAD, Nadia Mamoona; (GB).
LAI, Justine, Yeun Quai; (GB).
MARSHALL, Howard, Robert; (GB).
NASH, David, John; (GB).
PORTER, Roderick, Alan; (GB)
Agent: KONDO, Rie; GlaxoSmithKline, Corporate Intellectual Property (CN925.1), 980 Great West Road, Brentford, Middlesex TW8 9GS (GB)
Priority Data:
0701952.4 01.02.2007 GB
0701978.9 01.02.2007 GB
Title (EN) 8-OXA-1, 4-DIAZASPIRO [4,5] DEC-3-EN-1-YL AND 1,4, 8-TRIAZASPIRO [4,5] DEC- 3-EN-1-YL ACETAMIDES AS GLYTI TRANSPORTER INHIBITORS IN TREATMENT OF NEUROLOGICAL AND NEUROPSYCHIATRIC DISORDERS
(FR) INHIBITEURS DU TRANSPORTEUR GLYT1 ET LEURS UTILISATIONS DANS LE TRAITEMENT DE TROUBLES NEUROLOGIQUES ET NEUROPSYCHIATRIQUES
Abstract: front page image
(EN)Compounds of formula (I) or a salt thereof are provided wherein R1, R2, R3, R4, R5, R6, R7, R9, R10, X, n, p and m are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicament for treating neurological and neuropsychiatric disorders, in particular psychoses, dementia or attention deficit disorder are also disclosed. The invention further discloses pharmaceutical compositions and combinations comprising the compounds.
(FR)L'invention concerne des composés de formule (I) ou l'un de leurs sels, R1, R2, R3, R4, R5, R6, R7, R9, R10, X, n, p et m étant tels que définis dans la description. L'invention concerne également les utilisations des composés en tant que médicaments et dans la fabrication de médicaments destinés à traiter des troubles neurologiques et neuropsychiatriques, notamment des psychoses, une démence ou un trouble de déficit de l'attention. L'invention concerne en outre des compositions et des combinaisons pharmaceutiques comprenant les composés.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)