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1. (WO2008092844) PIPERIDIN-ACETAMIDE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY OR ALLERGIC DISEASES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2008/092844    International Application No.:    PCT/EP2008/051011
Publication Date: 07.08.2008 International Filing Date: 29.01.2008
IPC:
C07D 211/70 (2006.01), C07D 403/12 (2006.01), A61K 31/41 (2006.01), A61K 31/4409 (2006.01), A61K 31/4439 (2006.01), A61P 11/00 (2006.01), A61P 29/00 (2006.01), A61P 17/00 (2006.01), A61P 37/08 (2006.01)
Applicants: NOVARTIS AG [CH/CH]; Lichtstrasse 35, CH-4056 Basel (CH) (For All Designated States Except US).
LEHR, Philipp [DE/AT]; (AT) (For US Only).
WEIGAND, Klaus [DE/AT]; (AT) (For US Only).
COLSON, Anny-Odile [US/GB]; (GB) (For US Only)
Inventors: LEHR, Philipp; (AT).
WEIGAND, Klaus; (AT).
COLSON, Anny-Odile; (GB)
Agent: LETTENBICHLER, Isolde; Novartis Pharma AG, Patent Department, CH-4002 Basel (CH)
Priority Data:
07101466.6 31.01.2007 EP
Title (EN) PIPERIDIN-ACETAMIDE DERIVATIVES FOR THE TREATMENT OF INFLAMMATORY OR ALLERGIC DISEASES
(FR) DÉRIVÉS DE PIPÉRIDINE-ACÉTAMIDE POUR LE TRAITEMENT DE MALADIES INFLAMMATOIRES OU ALLERGIQUES
Abstract: front page image
(EN)A compound of formula (I), wherein substituents are as given above, useful in the treatment of a disease mediated by the action of CCR3, wherein R1 and R2 independently are (C6-18)aryl or (C6-18)aryl(C1-6)alkyl one or morefold substituted by (C1-6)alkyl, C(1-6)aIkoxy, halo(C1-6)alkyl, halogen or unsubstituted or substituted heterocyclyl having 5 or 6 ring members and 1 to 4 heteroatoms selected from N, O, S.
(FR)L'invention porte sur un composé de formule (I), dans laquelle les substituants sont tels qu'indiqués ci-dessus, qui s'utilise dans le traitement d'une maladie à médiation par l'action de CCR3, R1 et R2 représentant indépendamment l'aryle en C6-18 ou l'aryl en C6-18-alkyle en C1-6 une ou plusieurs fois substitués par l'alkyle en C1-6, l'alcoxy en C1-6, l'halo-alkyle en C1-6, l'halogène ou l'hétérocyclyle non substitué ou substitué ayant 5 ou 6 chaînons et 1 à 4 hétéroatomes choisis parmi N, O, S.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, SV, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MT, NL, NO, PL, PT, RO, SE, SI, SK, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)